{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T00:11:35Z","timestamp":1794010295912,"version":"4.8.0"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,12,19]],"date-time":"2016-12-19T00:00:00Z","timestamp":1482105600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/Objectives<\/jats:title><jats:p>Rocky Mountain spotted fever (<jats:styled-content style=\"fixed-case\">RMSF<\/jats:styled-content>), a lethal tick\u2010borne illness, is prevalent in the south central United States. Children younger than 10 years old have the greatest risk of fatal outcome from <jats:styled-content style=\"fixed-case\">RMSF<\/jats:styled-content>. The objective of the current study was to review pediatric cases of <jats:styled-content style=\"fixed-case\">RMSF<\/jats:styled-content> seen in the dermatology consult service and to evaluate dermatology's role in the diagnosis and management of this disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review was performed of inpatient dermatology consultations at a tertiary care center in North Carolina from 2001 to 2011. Data collected included patient demographic characteristics, symptoms, pre\u2010 and postconsultation diagnoses, diagnostic procedures, length of hospital stay, and outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 3,912 consultations were conducted in the dermatology service over 10 years. Six patients with <jats:styled-content style=\"fixed-case\">RMSF<\/jats:styled-content>, ranging in age from 22 months to 10 years (mean 5.1 years), were evaluated during April, May, and June. All preconsultation diagnoses included <jats:styled-content style=\"fixed-case\">RMSF<\/jats:styled-content> in the differential diagnosis. All patients underwent skin biopsies, and a culture was obtained in one case. Fifty percent of patients died within 4 days of hospitalization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Variables associated with mortality from <jats:styled-content style=\"fixed-case\">RMSF<\/jats:styled-content> are delayed diagnosis and initiation of antirickettsial therapy. Physicians should consider <jats:styled-content style=\"fixed-case\">RMSF<\/jats:styled-content> in children presenting with fever and rash during the summer months. Dermatology consultation is useful in evaluating patients with suspicious clinical features of <jats:styled-content style=\"fixed-case\">RMSF<\/jats:styled-content> with skin findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pde.13053","type":"journal-article","created":{"date-parts":[[2016,12,19]],"date-time":"2016-12-19T06:16:51Z","timestamp":1482128211000},"page":"119-123","source":"Crossref","is-referenced-by-count":10,"title":["Retrospective Study of Rocky Mountain Spotted Fever in Children"],"prefix":"10.1111","volume":"34","author":[{"given":"Rechelle","family":"Tull","sequence":"first","affiliation":[{"name":"Department of Dermatology School of Medicine Wake Forest University Winston\u2010Salem North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine Wake Forest University Winston\u2010Salem North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa","family":"Daniel","sequence":"additional","affiliation":[{"name":"Mecklenburg Medical Group\u2010Southpark Charlotte North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gil","family":"Yosipovitch","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine Temple University Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsay C.","family":"Strowd","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine Wake Forest University Winston\u2010Salem North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,12,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.7.769"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2003.tb07331.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/150.4.480"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2010.09-0752"},{"key":"e_1_2_7_6_1","first-page":"1","article-title":"Division of Notifiable Diseases and Healthcare Information, Office of Surveillance, Epidemiology, and Laboratory Services, CDC. 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