{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:20:10Z","timestamp":1740126010302,"version":"3.37.3"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,5,19]],"date-time":"2017-05-19T00:00:00Z","timestamp":1495152000000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2017,5]]},"abstract":"Abstract<\/jats:title>Objectives<\/jats:title>To identify endocrinologic problems, particularly those concerning growth, in collodion babies (CB<\/jats:styled-content>s).<\/jats:p><\/jats:sec>Methods<\/jats:title>Clinically identified newborn CB<\/jats:styled-content>s were included in the study group (group 1). Because CB<\/jats:styled-content>s are generally born premature, small for gestational age (SGA<\/jats:styled-content>), or both, a control group matched to the study group in terms of gestational age and birthweight (group 2) was also established. Blood specimens were collected from both groups for thyroid function tests and to measure serum growth hormone (GH<\/jats:styled-content>), insulinlike growth factor 1 (IGF<\/jats:styled-content>\u20101) and IGF<\/jats:styled-content> binding protein\u20103\u00a0(IGFBP<\/jats:styled-content>\u20103) levels.<\/jats:p><\/jats:sec>Results<\/jats:title>Group 1 consisted of 42 CB<\/jats:styled-content>s (25 male, 17 female) with gestational ages of 32 to 42\u00a0weeks and birthweights of 1,400 to 4,000\u00a0g. Twelve were assessed as premature and 17 as SGA<\/jats:styled-content>. Serum IGF<\/jats:styled-content>\u20101 and IGFBP<\/jats:styled-content>\u20103 levels were lower and serum GH<\/jats:styled-content> levels higher than in controls. Primary hypothyroidism was diagnosed in 10 patients in the study group, subclinical hypothyroidism in 2, and central hypothyroidism in 1. A statistically significant difference was determined between the groups in terms of primary hypothyroidism (p\u00a0=\u00a00.01). Serum GH<\/jats:styled-content> levels were weakly negatively correlated with birthweight (correlation coefficient [r<\/jats:italic>]\u00a0=\u00a0\u22120.32, p\u00a0=\u00a00.04) and serum IGF<\/jats:styled-content>\u20101 (r<\/jats:italic>\u00a0=\u00a0\u22120.38, p\u00a0=\u00a00.001) and IGFBP<\/jats:styled-content>\u20103 (r<\/jats:italic>\u00a0=\u00a0\u22120.36, p\u00a0=\u00a00.002) levels.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Premature birth and SGA<\/jats:styled-content> are common in CB<\/jats:styled-content>s. GH<\/jats:styled-content> levels are high and IGF<\/jats:styled-content>\u20101 and IGFBP<\/jats:styled-content>\u20103 levels low at birth as a sign of GH<\/jats:styled-content> resistance in these patients. The greater prevalence of hypothyroidism in these children is also significant.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pde.13120","type":"journal-article","created":{"date-parts":[[2017,5,19]],"date-time":"2017-05-19T07:41:27Z","timestamp":1495179687000},"page":"290-294","source":"Crossref","is-referenced-by-count":1,"title":["Neonatal Endocrinologic Problems in Collodion Babies"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7572-069X","authenticated-orcid":false,"given":"Ahmet","family":"Ozdemir","sequence":"first","affiliation":[{"name":"Division of Neonatology Department of Pediatrics Faculty of Medicine Erciyes University Kayseri Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabriye","family":"Korkut","sequence":"additional","affiliation":[{"name":"Division of Neonatology Department of Pediatrics Faculty of Medicine Erciyes University Kayseri Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selim","family":"Kurtoglu","sequence":"additional","affiliation":[{"name":"Division of Neonatology Department of Pediatrics Faculty of Medicine Erciyes University Kayseri Turkey"},{"name":"Division of Pediatric Endocrinology Department of Pediatrics Faculty of Medicine Erciyes University Kayseri Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nihal","family":"Hatipoglu","sequence":"additional","affiliation":[{"name":"Division of Pediatric Endocrinology Department of Pediatrics Faculty of Medicine Erciyes University Kayseri Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamer","family":"Gunes","sequence":"additional","affiliation":[{"name":"Division of Neonatology Department of Pediatrics Faculty of Medicine Erciyes University Kayseri Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Adnan","family":"Ozturk","sequence":"additional","affiliation":[{"name":"Division of Neonatology Department of Pediatrics Faculty of Medicine Erciyes University Kayseri Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,5,19]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.11.020"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200304020-00002"},{"key":"e_1_2_5_4_1","first-page":"55","article-title":"A retrospective study on 16 collodion babies","volume":"39","author":"Ozturk A","year":"1997","journal-title":"Turk J Pediatr"},{"key":"e_1_2_5_5_1","first-page":"8","article-title":"Family burden in inherited ichthyosis: creation of a specific questionnaire","volume":"15","author":"Dufresne H","year":"2013","journal-title":"Orphanet J Rare Dis"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2013.25.4.483"},{"key":"e_1_2_5_7_1","first-page":"439","article-title":"Updated AAP guidelines on newborn screening and therapy for congenital hypothyroidism","volume":"76","author":"Smith L","year":"2007","journal-title":"Am Fam Physician"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2009.05.002"},{"key":"e_1_2_5_9_1","first-page":"174","article-title":"Familial thyroxin\u2010binding globulin excess with ichthyosis: a case report","volume":"46","author":"Onenli\u2010Mungan N","year":"2004","journal-title":"Turk J Pediatr"},{"volume-title":"Pediatric endocrinology","year":"2000","author":"Fisher DA","key":"e_1_2_5_10_1"},{"key":"e_1_2_5_11_1","first-page":"289","article-title":"The association between hypothyroidism and other congenital defects. 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