{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T20:01:58Z","timestamp":1759089718789,"version":"3.37.3"},"reference-count":9,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,9,8]],"date-time":"2017-09-08T00:00:00Z","timestamp":1504828800000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Granulomatosis with polyangiitis (<jats:styled-content style=\"fixed-case\">GPA<\/jats:styled-content>), a vasculitis that most commonly affects small to medium\u2010size vessels of the respiratory tract and kidneys, may also present with a wide array of skin findings. We present the case of a 12\u2010year\u2010old boy with pyoderma gangrenosum\u2013like ulcerations on his lower extremity as the initial manifestation of <jats:styled-content style=\"fixed-case\">GPA<\/jats:styled-content> despite negative cytoplasmic antineutrophilic cytoplasmic antibodies (c\u2010<jats:styled-content style=\"fixed-case\">ANCA<\/jats:styled-content>s). Although <jats:styled-content style=\"fixed-case\">GPA<\/jats:styled-content> is strongly associated with c\u2010<jats:styled-content style=\"fixed-case\">ANCA<\/jats:styled-content>, c\u2010<jats:styled-content style=\"fixed-case\">ANCA<\/jats:styled-content> may be negative on presentation. Thus clinical and pathologic clues must be relied upon when serologic confirmation is negative.<\/jats:p>","DOI":"10.1111\/pde.13230","type":"journal-article","created":{"date-parts":[[2017,9,8]],"date-time":"2017-09-08T11:20:49Z","timestamp":1504869649000},"source":"Crossref","is-referenced-by-count":7,"title":["Granulomatosis with Polyangiitis Presenting with Pyoderma Gangrenosum\u2013Like Ulceration and Negative Cytoplasmic Antineutrophilic Cytoplasmic Antibodies in a Child"],"prefix":"10.1111","volume":"34","author":[{"given":"Ashley","family":"Kass","sequence":"first","affiliation":[{"name":"Philadelphia College of Medicine Philadelphia Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8992-866X","authenticated-orcid":false,"given":"Jake D.","family":"Fagan","sequence":"additional","affiliation":[{"name":"Geisinger Health System Danville Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Long","sequence":"additional","affiliation":[{"name":"Geisinger Health System Danville Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,9,8]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.01.043"},{"key":"e_1_2_5_3_1","first-page":"517025","article-title":"Cutaneous ulcers as initial presentation of localized granulomatosis with polyangiitis: a case report and review of the literature","volume":"2015","author":"Nasir N","year":"2015","journal-title":"Case Report Rheumatol"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780370206"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1994.tb02858.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2005.01.014"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2006.00699.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69114-9"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(94)70224-1"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/2229-5178.93482"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.13230","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13230","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T16:27:50Z","timestamp":1695572870000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.13230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1111\/pde.13230"],"URL":"https:\/\/doi.org\/10.1111\/pde.13230","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"type":"print","value":"0736-8046"},{"type":"electronic","value":"1525-1470"}],"subject":[],"published":{"date-parts":[[2017,9]]}}}