{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T11:20:25Z","timestamp":1780572025115,"version":"3.54.1"},"reference-count":5,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,9,21]],"date-time":"2017-09-21T00:00:00Z","timestamp":1505952000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report the case of a 2\u2010year\u2010old boy with Hirschsprung's disease who developed perianal pseudoverrucous papules and nodules subsequent to persistent diarrhea and stool leakage after <jats:italic>Giardia<\/jats:italic> infection. Bleeding from the papules resulted in iron deficiency anaemia requiring blood transfusion and iron infusion. Topical therapies used over 6 months were of limited benefit and colostomy was considered, but the condition completely resolved after commencement of oral loperamide. This demonstrates that perianal pseudoverrucous papules and nodules can be severe but are entirely reversible upon removal of the source of skin irritation.<\/jats:p>","DOI":"10.1111\/pde.13275","type":"journal-article","created":{"date-parts":[[2017,9,22]],"date-time":"2017-09-22T02:06:47Z","timestamp":1506046007000},"source":"Crossref","is-referenced-by-count":8,"title":["Perianal pseudoverrucous papules and nodules in Hirschsprung's disease: Rapid resolution with oral loperamide"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8005-7319","authenticated-orcid":false,"given":"Francis H. X.","family":"Yap","sequence":"first","affiliation":[{"name":"Department of Dermatology Royal Perth Hospital Perth WA Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham","family":"Thom","sequence":"additional","affiliation":[{"name":"Department of Dermatology Princess Margaret Hospital Perth WA Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,21]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)82008-6"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.12.025"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1992.01680120112014"},{"key":"e_1_2_3_5_1","first-page":"e98","article-title":"Loperamide therapy for acute diarrhea in children: systematic review and meta\u2010analysis","volume":"4","author":"Li ST","year":"2007","journal-title":"PLoS One"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2008.10.053"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.13275","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13275","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T09:48:37Z","timestamp":1695548917000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.13275"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,21]]},"references-count":5,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1111\/pde.13275"],"URL":"https:\/\/doi.org\/10.1111\/pde.13275","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,21]]}}}