{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T06:13:27Z","timestamp":1778825607349,"version":"3.51.4"},"reference-count":4,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,11,16]],"date-time":"2017-11-16T00:00:00Z","timestamp":1510790400000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Netherton syndrome is an autosomal recessive ichthyosis caused by mutations in <jats:italic>SPINK5<\/jats:italic>, with the classic triad of linearis circumflexa, trichorrhexis invaginata, and atopy. There are few reports of surgical management in individuals with Netherton syndrome and clinicians may be reluctant to operate for fear of wound\u2010healing complications. This report describes a pediatric case of a Buschke\u2013Lowenstein tumor of the natal cleft in a patient with Netherton syndrome that had failed to respond to medical management. We reviewed the literature for previous cases of surgery in individuals with Netherton syndrome using MEDLINE and PubMed searches. Our patient underwent surgery to remove the lesion without complication. Using conventional dressings and topical negative\u2010pressure therapy, the wound was managed and healed within a reasonable time frame despite the underlying skin condition. This case indicates that surgery and topical negative\u2010pressure therapy is a safe and reasonable treatment for individuals with Netherton syndrome.<\/jats:p>","DOI":"10.1111\/pde.13292","type":"journal-article","created":{"date-parts":[[2017,11,16]],"date-time":"2017-11-16T12:45:23Z","timestamp":1510836323000},"source":"Crossref","is-referenced-by-count":11,"title":["Considerations in surgical management of a Buschke\u2013Lowenstein tumor in Netherton syndrome: A case report"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5672-6594","authenticated-orcid":false,"given":"Rosalind","family":"Ashton","sequence":"first","affiliation":[{"name":"Division of Plastic Surgery University of Ottawa Ottawa ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamil","family":"Moledina","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery St. George's Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Branavan","family":"Sivakumar","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Great Ormond Street Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2670-8117","authenticated-orcid":false,"given":"Jemima E.","family":"Mellerio","sequence":"additional","affiliation":[{"name":"Department of Dermatology Great Ormond Street Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna E.","family":"Martinez","sequence":"additional","affiliation":[{"name":"Department of Dermatology Great Ormond Street Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,11,16]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781444345384.ch124"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2012.03815.x"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6815-13-7"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2011.03.013"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.13292","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13292","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T09:47:50Z","timestamp":1695548870000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.13292"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":4,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1111\/pde.13292"],"URL":"https:\/\/doi.org\/10.1111\/pde.13292","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11]]}}}