{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,28]],"date-time":"2025-12-28T16:40:44Z","timestamp":1766940044121,"version":"3.37.3"},"reference-count":5,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T00:00:00Z","timestamp":1521936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Epidermolysis bullosa simplex is a group of inherited disorders with allelic and locus heterogeneity in which skin fragility and blistering within the skin occur. Mutations in <jats:italic><jats:styled-content style=\"fixed-case\">KRT<\/jats:styled-content>5<\/jats:italic> and <jats:italic><jats:styled-content style=\"fixed-case\">KRT<\/jats:styled-content>14<\/jats:italic> underlie the majority of reported cases. Mutations in <jats:italic><jats:styled-content style=\"fixed-case\">KLHL<\/jats:styled-content>24<\/jats:italic>, a gene that encodes <jats:styled-content style=\"fixed-case\">KLHL<\/jats:styled-content>24 protein, have been reported recently to cause a generalized subtype of epidermolysis bullosa simplex, presumably by increasing the degradation of keratin 14. We describe a case of <jats:italic><jats:styled-content style=\"fixed-case\">KLHL<\/jats:styled-content>24<\/jats:italic>\u2010related epidermolysis bullosa simplex and highlight the burn\u2010like pattern of scars.<\/jats:p>","DOI":"10.1111\/pde.13443","type":"journal-article","created":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T17:06:18Z","timestamp":1521997578000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Burnlike scars: A sign suggestive of <scp>KLHL<\/scp>24\u2010related epidermolysis bullosa simplex"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9292-6369","authenticated-orcid":false,"given":"Azzam","family":"Alkhalifah","sequence":"first","affiliation":[{"name":"Department of Dermatology Nice University Hospital Nice France"},{"name":"Unaizah College of Medecine Qassim University Qassim Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Chiaverini","sequence":"additional","affiliation":[{"name":"Department of Dermatology Nice University Hospital Nice France"},{"name":"French Reference Center for Inherited Epidermolysis Bullosa CREBHN Nice University Hospital Nice France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Charlesworth","sequence":"additional","affiliation":[{"name":"French Reference Center for Inherited Epidermolysis Bullosa CREBHN Nice University Hospital Nice France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Has","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Medical Center Freiburg Freiburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Philippe","family":"Lacour","sequence":"additional","affiliation":[{"name":"Department of Dermatology Nice University Hospital Nice France"},{"name":"French Reference Center for Inherited Epidermolysis Bullosa CREBHN Nice University Hospital Nice France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,25]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.01.903"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-7364-7-13"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3701"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2016.11.005"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.01.004"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.13443","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13443","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T23:13:41Z","timestamp":1695510821000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.13443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,25]]},"references-count":5,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["10.1111\/pde.13443"],"URL":"https:\/\/doi.org\/10.1111\/pde.13443","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"type":"print","value":"0736-8046"},{"type":"electronic","value":"1525-1470"}],"subject":[],"published":{"date-parts":[[2018,3,25]]},"assertion":[{"value":"2018-03-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}