{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:19:36Z","timestamp":1791472776811,"version":"4.3.4"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,4,25]],"date-time":"2018-04-25T00:00:00Z","timestamp":1524614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Langerhans cell histiocytosis is a rare group of disorders that results from the abnormal proliferation and accumulation of dendritic\u2010derived cells in various organs of the body, such as the skin and bones. Hypopigmented macules are a rare cutaneous presentation of Langerhans cell histiocytosis that may pose a diagnostic dilemma when no other findings of Langerhans cell histiocytosis are present at the time of examination. We present 2 cases of the hypopigmented variant of Langerhans cell histiocytosis, including a case with histopathologic features of regression, and a review of the literature. These cases highlight the importance of including Langerhans cell histiocytosis in the differential diagnosis of an infant with hypopigmented macules and papules.<\/jats:p>","DOI":"10.1111\/pde.13509","type":"journal-article","created":{"date-parts":[[2018,4,25]],"date-time":"2018-04-25T08:08:18Z","timestamp":1524643698000},"page":"502-506","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Cutaneous Langerhans cell histiocytosis presenting with hypopigmented lesions: Report of two cases and review of literature"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3745-7368","authenticated-orcid":false,"given":"Shoko","family":"Mori","sequence":"first","affiliation":[{"name":"Department of Dermatology State University of New York Downstate Medical Center Brooklyn NY 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