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Preliminary studies have demonstrated mosaic activating mutations in <jats:styled-content style=\"fixed-case\">PIK<\/jats:styled-content>3<jats:styled-content style=\"fixed-case\">CA<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/pde.13514","type":"journal-article","created":{"date-parts":[[2018,5,16]],"date-time":"2018-05-16T06:59:49Z","timestamp":1526453989000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Lower lip capillary malformation associated with lymphatic malformation without overgrowth: Part of the spectrum of <scp>CLAPO<\/scp> syndrome"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1624-1170","authenticated-orcid":false,"given":"Camila","family":"Downey","sequence":"first","affiliation":[{"name":"Department of Dermatology Hospital de la Santa Creu i Sant Pau Universitat Aut\u00f3noma de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"L\u00f3pez\u2010Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Vascular Anomalies Center University Hospital La Paz Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Ro\u00e9\u2010Crespo","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital de la Santa Creu i Sant Pau Universitat Aut\u00f3noma de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Puig","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital de la Santa Creu i Sant Pau Universitat Aut\u00f3noma de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eulalia","family":"Baselga","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital de la Santa Creu i Sant Pau Universitat Aut\u00f3noma de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,5,15]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32517"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13244"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.09.045"},{"key":"e_1_2_2_5_1","unstructured":"RodriguezLaguna L L\u00f3pez\u2010Guti\u00e9rrezJ Mart\u00edn\u2010ArenasR et\u00a0al.Somatic activating PIK3CA mutations cause CLAPO syndrome. 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