{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T15:30:14Z","timestamp":1759937414225,"version":"3.37.3"},"reference-count":8,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T00:00:00Z","timestamp":1535673600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A male infant born at 32 weeks\u2019 gestation with a birthweight of 1030 g was started on intravenous vancomycin for a femoral osteomyelitis. On day 7 of treatment, he developed an erythematous flushed rash, rapidly spreading from the head to trunk and extremities, and became markedly irritable; vancomycin infusion was promptly stopped, with subsequent skin clearance. Given the wide use of vancomycin for the treatment of neonatal infections, a good awareness of red man syndrome signs and symptoms in the neonatal population is fundamental to recognize this adverse drug reaction and manage its rare but possible life\u2010threatening complications.<\/jats:p>","DOI":"10.1111\/pde.13654","type":"journal-article","created":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T07:49:51Z","timestamp":1535701791000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Vancomycin\u2010induced red man syndrome presentation in a preterm infant"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2078-7114","authenticated-orcid":false,"given":"Silvia","family":"Martini","sequence":"first","affiliation":[{"name":"Neonatology and Neonatal Intensive Care Unit Department of Medical and Surgical Sciences (DIMEC) St. Orsola\u2010Malpighi Hospital\u2014University of Bologna Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosina","family":"Alessandroni","sequence":"additional","affiliation":[{"name":"Neonatology and Neonatal Intensive Care Unit Department of Medical and Surgical Sciences (DIMEC) St. Orsola\u2010Malpighi Hospital\u2014University of Bologna Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santo","family":"Arcuri","sequence":"additional","affiliation":[{"name":"Neonatology and Neonatal Intensive Care Unit Department of Medical and Surgical Sciences (DIMEC) St. Orsola\u2010Malpighi Hospital\u2014University of Bologna Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giacomo","family":"Faldella","sequence":"additional","affiliation":[{"name":"Neonatology and Neonatal Intensive Care Unit Department of Medical and Surgical Sciences (DIMEC) St. Orsola\u2010Malpighi Hospital\u2014University of Bologna Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,8,31]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/157.3.502"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.86.4.572"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31824e10d7"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2012.10.003"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11096-011-9593-z"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000237305"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2016.12.022"},{"key":"e_1_2_3_9_1","unstructured":"TOXNET\u2014Toxicology Data Network website.Diphenhydramine.http:\/\/toxnet.nlm.nih.gov\/cgi-bin\/sis\/search\/a?dbs+hsdb%3A%40term+%40DOCNO+3066. Updated September 4 2014. Accessed June 7 2018."}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.13654","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13654","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T10:46:26Z","timestamp":1694861186000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.13654"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,31]]},"references-count":8,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1111\/pde.13654"],"URL":"https:\/\/doi.org\/10.1111\/pde.13654","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"type":"print","value":"0736-8046"},{"type":"electronic","value":"1525-1470"}],"subject":[],"published":{"date-parts":[[2018,8,31]]},"assertion":[{"value":"2018-08-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}