{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T20:13:49Z","timestamp":1779221629344,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,11,26]],"date-time":"2018-11-26T00:00:00Z","timestamp":1543190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Drug\u2010induced reactions are complications associated with high mortality and significant morbidity. Stevens\u2013Johnson Syndrome (<jats:styled-content style=\"fixed-case\">SJS<\/jats:styled-content>) and toxic epidermal necrolysis (<jats:styled-content style=\"fixed-case\">TEN<\/jats:styled-content>) are examples of these conditions, which are characterized by skin and mucous lesions. Here, we report a case of a 9\u2010year\u2010old girl who presented with blisters associated with an extensive vesicular rash and multiple ulcerations on the lips and oral cavity. A drug\u2010induced hypersensitivity reaction to antibiotics was suspected, and a diagnosis of <jats:styled-content style=\"fixed-case\">TEN<\/jats:styled-content> was made. The patient was managed with withdrawal of the suspected causative agent, and the oral lesions were treated with low\u2010level laser therapy (<jats:styled-content style=\"fixed-case\">LLLT<\/jats:styled-content>) and oral hygiene. This case highlights that <jats:styled-content style=\"fixed-case\">TEN<\/jats:styled-content> requires interdisciplinary intervention with dental assistance and follow\u2010up to improve symptoms, nutrition, systemic condition, and quality of life.<\/jats:p>","DOI":"10.1111\/pde.13719","type":"journal-article","created":{"date-parts":[[2018,11,26]],"date-time":"2018-11-26T11:12:31Z","timestamp":1543230751000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Treatment of oral manifestations of toxic epidermal necrolysis with low\u2010level laser therapy in a pediatric patient"],"prefix":"10.1111","volume":"36","author":[{"given":"Amanda Leal","family":"Rocha","sequence":"first","affiliation":[{"name":"Department of Oral Surgery and Pathology Faculty of Dentistry Universidade Federal de Minas Gerais Belo Horizonte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra Figueiredo De","family":"Souza","sequence":"additional","affiliation":[{"name":"Department of Community and Preventive Dentistry Faculty of Dentistry Universidade Federal de Minas Gerais Belo Horizonte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laiz Fernandes Mendes","family":"Nunes","sequence":"additional","affiliation":[{"name":"Dental Surgeon Resident Hospital das Clinicas Universidade Federal de Minas Gerais Belo Horizonte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nayara Dias de Souza","family":"Cunha","sequence":"additional","affiliation":[{"name":"Department of Medicine Hospital das Clinicas Universidade Federal de Minas Gerais Belo Horizonte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9lia Regina Moreira","family":"Lanza","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Pathology Faculty of Dentistry Universidade Federal de Minas Gerais Belo Horizonte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise Vieira","family":"Travassos","sequence":"additional","affiliation":[{"name":"Department of Community and Preventive Dentistry Faculty of Dentistry Universidade Federal de Minas Gerais Belo Horizonte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9623-7835","authenticated-orcid":false,"given":"Tarc\u00edlia Aparecida da","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Pathology Faculty of Dentistry Universidade Federal de Minas Gerais Belo Horizonte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,11,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2017.0160"},{"issue":"2","key":"e_1_2_5_3_1","first-page":"185","article-title":"Toxic epidermal necrolysis. 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