{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:27:38Z","timestamp":1780471658085,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,2,10]],"date-time":"2019-02-10T00:00:00Z","timestamp":1549756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Parry\u2010Romberg syndrome (<jats:styled-content style=\"fixed-case\">PRS<\/jats:styled-content>) is characterized by hemiatrophy of facial structures, including skin, subcutaneous fat, muscle, bone, and cartilage. Complications associated with <jats:styled-content style=\"fixed-case\">PRS<\/jats:styled-content> include headaches, seizures, and chronic facial pain. Protocol for the treatment of chronic facial pain is not clear; reports on the use of botulinum toxin A injections for pain reduction in adults but not in the pediatric\/adolescent population are available. Here, we discuss two pediatric <jats:styled-content style=\"fixed-case\">PRS<\/jats:styled-content> cases in which treatment with botulinum toxin A injections reduced or eliminated facial pain.<\/jats:p>","DOI":"10.1111\/pde.13746","type":"journal-article","created":{"date-parts":[[2019,2,11]],"date-time":"2019-02-11T00:35:15Z","timestamp":1549845315000},"page":"223-226","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Botulinum toxin A for pain reduction in pediatric patients with Parry\u2010Romberg syndrome"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7569-8699","authenticated-orcid":false,"given":"Kriti","family":"Mishra","sequence":"first","affiliation":[{"name":"School of Medicine University of New Mexico Albuquerque New Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun","family":"Sood","sequence":"additional","affiliation":[{"name":"Pediatric Dermatology Phoenix Children's Hospital Phoenix Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aimee","family":"Smidt","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of New Mexico Albuquerque New Mexico"},{"name":"Department of Pediatrics University of New Mexico Albuquerque New Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harper N.","family":"Price","sequence":"additional","affiliation":[{"name":"Pediatric Dermatology Phoenix Children's Hospital Phoenix Arizona"},{"name":"College of Medicine University of Arizona Phoenix Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,10]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-015-0250-9"},{"issue":"1","key":"e_1_2_4_3_1","first-page":"73","article-title":"The epidemiology of morphea (localized scleroderma) in Olmsted County 1960\u20101993","volume":"24","author":"Peterson LS","year":"1997","journal-title":"J Rheumatol"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.61.5.674"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2012.08.020"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/691314"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0b013e31828de9c0"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000001147"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-012-0459-0"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2011.126"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.4076\/1757-1626-2-6776"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.012211"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxins9090260"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2003.10.008"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0901-5027(88)80044-4"},{"issue":"9","key":"e_1_2_4_16_1","first-page":"1007","article-title":"A case of unilateral lingual atrophy and ipsilateral muscular atrophy supplied by trigeminal nerve\u2013in relation to progressive facial hemiatrophy","volume":"31","author":"Tsuda N","year":"1991","journal-title":"Rinsho Shinkeigaku (Clin Neurol)"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1981.00510090086013"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.60343"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamafacial.2013.2458"},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-014-1740-6"},{"key":"e_1_2_4_21_1","unstructured":"Administration USFaD.Botox Medication Guide. 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