{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:19:42Z","timestamp":1762431582865,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,2,11]],"date-time":"2019-02-11T00:00:00Z","timestamp":1549843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Lichen nitidus (<jats:styled-content style=\"fixed-case\">LN<\/jats:styled-content>) is an uncommon inflammatory skin eruption. The present study aims to describe a case series of children with <jats:styled-content style=\"fixed-case\">LN<\/jats:styled-content> seen at a tertiary\u2010care health center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective study of 17 children with biopsy\u2010proven <jats:styled-content style=\"fixed-case\">LN<\/jats:styled-content> between January 2007 and March 2017. Data related with epidemiologic, clinical, and histopathologic characteristics were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age for the onset of <jats:styled-content style=\"fixed-case\">LN<\/jats:styled-content> was 9\u00a0years (range: 5\u201017\u00a0years), and the mean duration of the skin lesions was 13\u00a0months (range: 1\u201048\u00a0months). Fifteen were boys (88.2%). Seven children had a generalized form of <jats:styled-content style=\"fixed-case\">LN<\/jats:styled-content> (41.1%) and of these, two children had severe pruritus (11.8%). Seven children had a history of co\u2010morbid skin conditions (41.1%), including lichen planus in one patient (5.9%), lichen striatus in one patient (5.9%), psoriasis and longitudinal ridges in the nails in one patient (5.9%), and cutaneous features of atopic skin in four patients (23.5%). All of the reviewed patients had lymphohistiocytic infiltration in the dermis and basal vacuolar degeneration. Multinucleated giant cells were present in 11 (64.7%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This case series found <jats:styled-content style=\"fixed-case\">LN<\/jats:styled-content> in a generalized form as well as other concurrent dermatologic conditions in nearly half of those reported. The boy predominance was also noteworthy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pde.13749","type":"journal-article","created":{"date-parts":[[2019,2,12]],"date-time":"2019-02-12T06:55:22Z","timestamp":1549954522000},"page":"189-192","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Pediatric lichen nitidus: A single\u2010center experience"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6061-925X","authenticated-orcid":false,"given":"Selcen","family":"Kundak","sequence":"first","affiliation":[{"name":"Department of Dermatology Dr. Behcet Uz Children's Research and Training Hospital Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasemin","family":"\u00c7ak\u0131r","sequence":"additional","affiliation":[{"name":"Department of Pathology Dr. Behcet Uz Children's Research and Training Hospital Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,2,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962012000300018"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2014.26.4.505"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.196316"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2015.12.008"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.44794"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.156398"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12356"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.5114\/ada.2016.63890"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20132829"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/0377-4929.59215"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.57738"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.01933.x"},{"issue":"7","key":"e_1_2_6_14_1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.5070\/D365P7C1S7","article-title":"Letter: generalized lichen nitidus successfully treated with pimecrolimus 1 percent cream","volume":"17","author":"Farshi S","year":"2011","journal-title":"Dermatol Online J"},{"key":"e_1_2_6_15_1","first-page":"982084","article-title":"Generalized lichen nitidus in identical twins","volume":"2012","author":"Leung AK","year":"2012","journal-title":"Case Rep Dermatol Med"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00417526"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(92)70176-G"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2007.00485.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1995.tb03419.x"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.13749","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13749","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.13749","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13749","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T04:37:39Z","timestamp":1694407059000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.13749"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,11]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1111\/pde.13749"],"URL":"https:\/\/doi.org\/10.1111\/pde.13749","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"type":"print","value":"0736-8046"},{"type":"electronic","value":"1525-1470"}],"subject":[],"published":{"date-parts":[[2019,2,11]]},"assertion":[{"value":"2019-02-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}