{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:26:09Z","timestamp":1771467969879,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,2,22]],"date-time":"2019-02-22T00:00:00Z","timestamp":1550793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR001117"],"award-info":[{"award-number":["UL1TR001117"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To quantify complications and rates of adverse events associated with surgical excision of hemangiomas in children using a national surgical database.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data source<\/jats:title><jats:p>Pediatric American College of Surgeons (<jats:styled-content style=\"fixed-case\">ACS<\/jats:styled-content>) National Surgical Quality Improvement Program<jats:sup>\u00ae<\/jats:sup> (<jats:styled-content style=\"fixed-case\">ACS NSQIP<\/jats:styled-content><jats:sup>\u00ae<\/jats:sup>\u2010pediatric), years 2012\u20102016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Subjects included children under 18\u00a0years with a postoperative diagnosis of International Classification of Diseases (<jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content>), 9th revision code: 228.00 and 228.01, or <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> 10 codes D18.00 and D18.01\u2014hemangioma, any site and hemangioma, of skin and subcutaneous tissue.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1180 patients were included. The median age was 3.2\u00a0years (interquartile range [<jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>] 1.2 to 6.4\u00a0years old). No occurrences of deep incisional surgical site infection, nerve injury, mortality, sepsis, septic shock, or blood stream infections were noted. In multivariate analysis, age \u2264 3\u00a0years and advanced American Society of Anesthesiologists class were significant predictors of adverse events (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.035 and 0.001, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>For children with infantile hemangioma who fail to respond or have an incomplete response to medical therapy, surgical resection may be a relatively safe treatment alternative. Children older than 3\u00a0years of age with hemangiomas had less surgical adverse events than younger children. Overall, however, the surgical complications rates were low and deemed relatively minor.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pde.13751","type":"journal-article","created":{"date-parts":[[2019,2,22]],"date-time":"2019-02-22T12:47:07Z","timestamp":1550839627000},"page":"207-212","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Outcomes of surgical treatment for hemangiomas"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7243-288X","authenticated-orcid":false,"given":"Jeffrey","family":"Cheng","sequence":"first","affiliation":[{"name":"Pediatric Otolaryngology Division of Head and Neck Surgery and Communication Sciences Department of Surgery Duke University Medical Center Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beiyu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Biostatistics &amp; Bioinformatics Duke University Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui\u2010Jie","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Biostatistics &amp; Bioinformatics Duke University Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,2,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-2482"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-3896"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.12788\/j.sder.2016.050"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016-0353"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc0708819"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1404710"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-00495-z"},{"key":"e_1_2_6_9_1","first-page":"5821369","article-title":"Effects of propranolol on neurodevelopmental outcomes in patients with infantile hemangioma: a case\u2010control study","volume":"2018","author":"Wang C","year":"2018","journal-title":"Biomed Res Int"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2017.09.010"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12928"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000002016"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-016-3643-6"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.13751","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13751","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.13751","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13751","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T04:37:41Z","timestamp":1694407061000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.13751"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,22]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1111\/pde.13751"],"URL":"https:\/\/doi.org\/10.1111\/pde.13751","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,22]]},"assertion":[{"value":"2019-02-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}