{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:18:14Z","timestamp":1787015894221,"version":"build-2736575974"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,3,4]],"date-time":"2019-03-04T00:00:00Z","timestamp":1551657600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Successful management of toxic epidermal necrolysis (\n                    <jats:styled-content style=\"fixed-case\">TEN<\/jats:styled-content>\n                    ) with tumor necrosis factor\u2010\u03b1 inhibitors has been described in adults. We present a case of a 7\u2010year\u2010old boy with infection\u2010associated\n                    <jats:styled-content style=\"fixed-case\">TEN<\/jats:styled-content>\n                    , diagnosed by typical clinical and histopathological features, most likely caused by\n                    <jats:italic>Mycoplasma pneumoniae<\/jats:italic>\n                    . Treatment with a single dose of infliximab 5\u00a0mg\/kg intravenously on day 5 after the onset of symptoms was followed by cessation of all blister formation over 3\u00a0days and complete resolution within a week. Sequelae were mild, consisting of postinflammatory hyperpigmentation and dry eyes.\n                  <\/jats:p>","DOI":"10.1111\/pde.13778","type":"journal-article","created":{"date-parts":[[2019,3,4]],"date-time":"2019-03-04T21:46:51Z","timestamp":1551736011000},"page":"342-345","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Pediatric toxic epidermal necrolysis treated successfully with infliximab"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2268-8216","authenticated-orcid":false,"given":"Lana","family":"Chafranska","sequence":"first","affiliation":[{"name":"Departments of Dermatology Zealand University Hospital  Roskilde Denmark"},{"name":"Health Sciences Faculty University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ditte M.","family":"Saunte","sequence":"additional","affiliation":[{"name":"Departments of Dermatology Zealand University Hospital  Roskilde Denmark"},{"name":"Health Sciences Faculty University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nille","family":"Behrendt","sequence":"additional","affiliation":[{"name":"Health Sciences Faculty University of Copenhagen  Copenhagen Denmark"},{"name":"Pathology Zealand University Hospital  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrikka","family":"Nygaard","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Adolescent Medicine Copenhagen University Hospital, Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan J.","family":"Christensen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics N\u00e6stved Hospital  N\u00e6stved Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten","family":"Sand","sequence":"additional","affiliation":[{"name":"Department of Dermato\u2010Venereology &amp; Wound Healing Centre Bispebjerg Hospital  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor B.","family":"Jemec","sequence":"additional","affiliation":[{"name":"Departments of Dermatology Zealand University Hospital  Roskilde Denmark"},{"name":"Health Sciences Faculty University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,3,4]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-1923"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/pai.12121"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2006.00307.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxins6010194"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.04.044"},{"key":"e_1_2_4_7_1","first-page":"AB168","article-title":"Toxic epidermal necrolysis successfully treated with infliximab","volume":"66","author":"Scott\u2010Lang V","year":"2012","journal-title":"J Am Acad Dermatol"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0462"},{"key":"e_1_2_4_9_1","first-page":"61","article-title":"Toxic epidermal necrolysis successfully treated with infliximab","volume":"23","author":"Zarate\u2010Correa LC","year":"2013","journal-title":"J Investig Allergol Clin Immunol"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.291.6491.312"},{"key":"e_1_2_4_11_1","first-page":"270","article-title":"PCR versus serology for diagnosing Mycoplasma pneumoniae infection: a systematic review & meta\u2010analysis","volume":"134","author":"Zhang L","year":"2011","journal-title":"Indian J Med Res"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.46281-0"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001444"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-8-93"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.13778","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13778","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.13778","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13778","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T10:54:44Z","timestamp":1694343284000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.13778"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,4]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1111\/pde.13778"],"URL":"https:\/\/doi.org\/10.1111\/pde.13778","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.735401227.793576499","asserted-by":"object"}]},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,4]]},"assertion":[{"value":"2019-03-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}