{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T18:19:14Z","timestamp":1773685154992,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,3,13]],"date-time":"2019-03-13T00:00:00Z","timestamp":1552435200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NIH Cancer Center","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Neurocutaneous melanosis (<jats:styled-content style=\"fixed-case\">NCM<\/jats:styled-content>) is the condition of abnormal melanocyte deposition in the leptomeninges and brain parenchyma. Associated with congenital melanocytic nevi, <jats:styled-content style=\"fixed-case\">NCM<\/jats:styled-content> can result in neurologic deficits, hydrocephalus, and rarely, malignant transformation of cells. We present the case of a 16\u2010year\u2010old boy with <jats:styled-content style=\"fixed-case\">NCM<\/jats:styled-content> who developed malignant leptomeningeal melanoma following immunosuppression with a <jats:styled-content style=\"fixed-case\">TNF<\/jats:styled-content>\u03b1 inhibitor. To our knowledge, this is the first reported case of a patient with known <jats:styled-content style=\"fixed-case\">NCM<\/jats:styled-content> undergoing malignant transformation after anti\u2010<jats:styled-content style=\"fixed-case\">TNF<\/jats:styled-content> therapy for inflammatory bowel disease.<\/jats:p>","DOI":"10.1111\/pde.13804","type":"journal-article","created":{"date-parts":[[2019,3,14]],"date-time":"2019-03-14T04:29:19Z","timestamp":1552537759000},"page":"497-500","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Malignant transformation of neurocutaneous melanosis (<scp>NCM<\/scp>) following immunosuppression"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4664-670X","authenticated-orcid":false,"given":"Lauren R.","family":"Schaff","sequence":"first","affiliation":[{"name":"Department of Neurology Memorial Sloan Kettering Cancer Center  New York City New 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