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These malformations produce neurologic and ophthalmological symptoms including seizures and glaucoma. A premature male newborn without prenatal diagnosis presented with severe bilateral SWS and was started on systemic sirolimus and aspirin. The patient has remained seizure\u2010free for 23\u00a0months and demonstrated an excellent response to pulsed dye laser treatment.<\/jats:p>","DOI":"10.1111\/pde.13841","type":"journal-article","created":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T08:26:12Z","timestamp":1559031972000},"page":"524-527","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Preventive treatment with oral sirolimus and aspirin in a newborn with severe Sturge\u2010Weber syndrome"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8176-6010","authenticated-orcid":false,"given":"Paloma E.","family":"Triana Junco","sequence":"first","affiliation":[{"name":"Pediatric Surgery La Paz Children's Hospital  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"S\u00e1nchez\u2010Carpintero","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Dermatol\u00f3gica Internacional  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Carlos","family":"L\u00f3pez\u2010Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"Pediatric Surgery La Paz Children's Hospital  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,5,28]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1213507"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2018.04.005"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13203"},{"key":"e_1_2_5_5_1","first-page":"86","article-title":"Sirolimus in the treatment of vascular anomalies","volume":"27","author":"Triana P","year":"2017","journal-title":"Eur J Pediatr Surg"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.10.011"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/088307389501000113"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2014.12.002"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.5301\/ejo.5000322"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073812463607"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2009.174417"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-12-1020"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.4274\/jcrpe.2773"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200544080-00001"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40262-015-0340-9"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0773.2001.088001003.x"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharep.2016.01.005"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-017-0621-5"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-3257"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpde.13841","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13841","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.13841","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13841","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T21:25:11Z","timestamp":1694294711000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.13841"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,28]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1111\/pde.13841"],"URL":"https:\/\/doi.org\/10.1111\/pde.13841","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,28]]},"assertion":[{"value":"2019-05-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}