{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T01:17:48Z","timestamp":1783127868795,"version":"3.54.6"},"reference-count":4,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T00:00:00Z","timestamp":1558915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Lymphadenopathy is a common sign for drug reaction and eosinophilia with systemic symptoms (<jats:styled-content style=\"fixed-case\">DRESS<\/jats:styled-content>) syndrome, but hilar and mediastinal lymphadenopathy may be underreported. We describe a 7\u2010year\u2010old boy who started taking ethosuximide for absence seizures and presented with diffuse rash, fever, elevated transaminases, facial swelling, and hilar and mediastinal lymphadenopathy. His mediastinal lymphadenopathy was concerning for lymphoma, which led to more invasive testing to rule out malignancy. This report highlights an unusual and likely underreported presenting sign of <jats:styled-content style=\"fixed-case\">DRESS<\/jats:styled-content> syndrome in children.<\/jats:p>","DOI":"10.1111\/pde.13848","type":"journal-article","created":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T13:15:48Z","timestamp":1558962948000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Ethosuximide\u2010induced drug reaction with eosinophilia and systemic symptoms with mediastinal lymphadenopathy"],"prefix":"10.1111","volume":"36","author":[{"given":"Tyler","family":"Werbel","sequence":"first","affiliation":[{"name":"School of Medicine University of California San Diego  La Jolla California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Castrovinci","sequence":"additional","affiliation":[{"name":"Department of Professional Education Naval Medical Center San Diego  San Diego California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5115-9324","authenticated-orcid":false,"given":"James","family":"Contestable","sequence":"additional","affiliation":[{"name":"Department of Dermatology Naval Medical Center San Diego  San Diego California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,5,27]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12501"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.01.032"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2017.28.218.10828"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.907464"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13848","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.13848","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.13848","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T21:25:47Z","timestamp":1694294747000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.13848"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,27]]},"references-count":4,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1111\/pde.13848"],"URL":"https:\/\/doi.org\/10.1111\/pde.13848","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,27]]},"assertion":[{"value":"2019-05-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}