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We report a unique case of a 6\u2010year\u2010old boy with prolidase deficiency and Crohn's disease who presented with lower extremity ulcers. Cutaneous ulcers due to prolidase deficiency are historically resistant to treatment, and we report success with the novel use of topical tacrolimus.<\/jats:p>","DOI":"10.1111\/pde.13973","type":"journal-article","created":{"date-parts":[[2019,10,7]],"date-time":"2019-10-07T00:39:21Z","timestamp":1570408761000},"page":"926-928","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Topical tacrolimus therapy in the management of lower\u00a0extremity ulcers due to prolidase deficiency"],"prefix":"10.1111","volume":"36","author":[{"given":"Allison J.","family":"Good","sequence":"first","affiliation":[{"name":"University of Florida College of Medicine Gainesville Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1663-625X","authenticated-orcid":false,"given":"Colton B.","family":"Nielson","sequence":"additional","affiliation":[{"name":"Department of Dermatology University 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