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Given this finding, we suspect that waxing disrupted the epidermal barrier and, therefore, rendered the patient more susceptible to severe irritant contact dermatitis upon depilation. While there are reported cases of irritant contact dermatitis and chemical burns secondary to waxing or depilatory cream use in adults, a literature review found no reported cases of chemical burns in a pediatric patient or adult consequent to using these methods in tandem.<\/jats:p>","DOI":"10.1111\/pde.14060","type":"journal-article","created":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T09:36:26Z","timestamp":1574760986000},"page":"190-191","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Severe irritant reaction following sequential waxing and use of a chemical depilatory cream in an adolescent"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7694-1443","authenticated-orcid":false,"given":"Julianne","family":"Kiene","sequence":"first","affiliation":[{"name":"School of Medicine Georgetown University Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel E.","family":"Maiman","sequence":"additional","affiliation":[{"name":"Department of Dermatology MedStar Washington Hospital Center\/Georgetown University Hospital Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia Marie Carver","family":"DeKlotz","sequence":"additional","affiliation":[{"name":"School of Medicine Georgetown University Washington DC USA"},{"name":"Department of Dermatology MedStar Washington Hospital Center\/Georgetown University Hospital Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,11,26]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000058953.16695.A7"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70181-7"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2012.01000.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2004.06.013"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12283"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000493168"},{"key":"e_1_2_4_8_1","first-page":"22","article-title":"The clinical relevance of maintaining the functional integrity of the stratum corneum in both healthy and disease\u2010affected skin","volume":"4","author":"Del Rosso JQ","year":"2011","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000360009"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.14060","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.14060","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.14060","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T02:24:21Z","timestamp":1693362261000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.14060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,26]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1111\/pde.14060"],"URL":"https:\/\/doi.org\/10.1111\/pde.14060","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,26]]},"assertion":[{"value":"2019-11-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}