{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:02:37Z","timestamp":1780470157865,"version":"3.54.1"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T00:00:00Z","timestamp":1588636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/Objectives<\/jats:title><jats:p>To determine the prevalence of urticarial vasculitis (UV) in a pediatric systemic lupus erythematosus (pSLE) cohort of Arab ethnicity from Oman and to describe their demographic, clinical, and laboratory features.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective multicenter study among pediatric rheumatology centers in Oman over a 10\u2010year period from 2008 to 2018. Analyses were performed using univariate statistics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 148 pSLE under the age of 13\u00a0years were included of which 30% (n\u00a0=\u00a044) were men. The overall mean age at SLE diagnosis was 7.6\u00a0\u00b1\u00a03.5\u00a0years while the mean disease duration was 10.1\u00a0\u00b1\u00a05.4\u00a0years. UV was diagnosed in 36% (n\u00a0=\u00a053) of pSLE patients. Patients with pSLE and UV were more likely to be male\u00a0(57% vs 15%;<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001), diagnosed at a younger age (5.9 vs 8.5\u00a0years;<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001), have a family history of SLE (53% vs 36%;<jats:italic>P<\/jats:italic>\u00a0=\u00a0.044), and have associated conjunctivitis, (32% vs 5.3%;<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001) but less likely to have CNS involvement (7.6% vs 20%;<jats:italic>P<\/jats:italic>\u00a0=\u00a0.045) or hematological manifestations such as leukopenia (9.4% vs 24%;<jats:italic>P<\/jats:italic>\u00a0=\u00a0.028) and thrombocytopenia (5.7% vs 18%;<jats:italic>P<\/jats:italic>\u00a0=\u00a0.045). This subgroup was also more likely to be associated with low C3 complement count (94% vs 66%;<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a0.001) and positive cytoplasmic ANCA (11% vs 0%;<jats:italic>P<\/jats:italic>\u00a0=\u00a0.022).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We report a high occurrence of UV in a pSLE cohort associated with unique demographic, clinical, and laboratory features.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pde.14184","type":"journal-article","created":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T01:13:41Z","timestamp":1588727621000},"page":"651-655","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Urticarial vasculitis in pediatric systemic lupus erythematosus"],"prefix":"10.1111","volume":"37","author":[{"given":"Ahmed","family":"Al Kamzari","sequence":"first","affiliation":[{"name":"Child Health Department Oman Medical Specialty Board Muscat Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Buthaina","family":"Al Musalhi","sequence":"additional","affiliation":[{"name":"Dermatology Department Sultan Qaboos University Hospital Muscat Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8303-4991","authenticated-orcid":false,"given":"Safiya","family":"Al Abrawi","sequence":"additional","affiliation":[{"name":"Child Health Department Royal Hospital Muscat Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3626-4230","authenticated-orcid":false,"given":"Ibrahim","family":"Al\u2010Zakwani","sequence":"additional","affiliation":[{"name":"Pharmacology &amp; Clinical Pharmacy Department College of Medicine &amp; Health Sciences Sultan Qaboos University Muscat Oman"},{"name":"Gulf Health Research Muscat Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1189-1959","authenticated-orcid":false,"given":"Reem","family":"Abdwani","sequence":"additional","affiliation":[{"name":"Child Health Department College of Medicine &amp; Health Sciences Sultan Qaboos University Muscat Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2013.07.007"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.12673"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2174\/1872213X10666160219163502"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.4168\/aair.2017.9.3.212"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.07.068"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.38956"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-200001000-00005"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2006.02847.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/S0190-9622(24)00193-2","article-title":"Clinicopathologic correlation of hypocomplementemic and normocomplementemic urticarial vasculitis","volume":"38","author":"Davis MD","year":"1998","journal-title":"J Am Acad Dermatol"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780400928"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780390303"},{"key":"e_1_2_6_13_1","first-page":"340","article-title":"Hypocomplementemia with cutaneous vasculitis and arthritis. 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