{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T04:59:26Z","timestamp":1773982766603,"version":"3.50.1"},"reference-count":4,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,1,29]],"date-time":"2021-01-29T00:00:00Z","timestamp":1611878400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Omenn syndrome is a rare combined immunodeficiency mostly associated with <jats:italic>RAG1<\/jats:italic> and <jats:italic>RAG2<\/jats:italic> mutations; the clinical manifestations are well\u2010described and include neonatal erythroderma. Mortality due to opportunistic infections is a serious risk, and a timely diagnosis with a skin biopsy is an important part of the diagnostic workup. We wish to highlight key clinical features of Omenn syndrome and discuss the relevance of a skin biopsy.<\/jats:p>","DOI":"10.1111\/pde.14401","type":"journal-article","created":{"date-parts":[[2021,1,29]],"date-time":"2021-01-29T09:56:32Z","timestamp":1611914192000},"page":"541-543","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Diagnosing Omenn syndrome"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5466-3374","authenticated-orcid":false,"given":"Louise","family":"Cutts","sequence":"first","affiliation":[{"name":"St Helens and Knowsley Teaching Hospitals NHS Trust St Helens UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arti","family":"Bakshi","sequence":"additional","affiliation":[{"name":"Royal Liverpool and Broadgreen University Hospitals NHS Trust Liverpool UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maeve","family":"Walsh","sequence":"additional","affiliation":[{"name":"St Helens and Knowsley Teaching Hospitals NHS Trust St Helens UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Parslew","sequence":"additional","affiliation":[{"name":"Alder Hey Hospital NHS Foundation Trust Liverpool UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Eustace","sequence":"additional","affiliation":[{"name":"St Helens and Knowsley Teaching Hospitals NHS Trust St Helens UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsi.2011.05.002"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s100240010171"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2009.01344.x"},{"issue":"2","key":"e_1_2_5_5_1","first-page":"133","article-title":"Omenn's syndrome: a rare primary immunodeficiency disorder","volume":"7","author":"Elnour IB","year":"2007","journal-title":"Sultan Qaboos Univ Med J"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.14401","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.14401","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.14401","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T19:29:26Z","timestamp":1692300566000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.14401"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,29]]},"references-count":4,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/pde.14401"],"URL":"https:\/\/doi.org\/10.1111\/pde.14401","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,29]]},"assertion":[{"value":"2019-11-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}