{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T18:33:30Z","timestamp":1787682810587,"version":"build-2784847793"},"reference-count":7,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,12,4]],"date-time":"2020-12-04T00:00:00Z","timestamp":1607040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 10\u2010year\u2010old Guatemalan girl with past medical history of Epstein\u2010Barr virus\u2010associated smooth muscle tumors (EBV\u2010SMT) and combined immunodeficiency presented for evaluation of painful intraoral lesions. On examination, she was noted to have multiple, white to flesh\u2010colored, soft, flat\u2010topped papules, and plaques on the buccal and labial mucosa. Human papillomavirus type 13 was detected on PCR with PGMY primers of previously biopsied buccal tissue, confirming a diagnosis of Heck's disease (multifocal epithelial hyperplasia). We present an immunosuppressed, pediatric patient with two rare, virus\u2010associated neoplastic disorders that have not been previously reported to occur in the same individual.<\/jats:p>","DOI":"10.1111\/pde.14463","type":"journal-article","created":{"date-parts":[[2020,12,4]],"date-time":"2020-12-04T15:18:14Z","timestamp":1607095094000},"page":"257-259","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Heck\u2019s disease occurring after Epstein\u2010Barr virus\u2010associated smooth muscle tumors in an immunosuppressed child"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0277-378X","authenticated-orcid":false,"given":"Natasha","family":"Arbelo\u2010Ramos","sequence":"first","affiliation":[{"name":"Department of Pediatric and Adolescent Medicine Mayo Clinic  Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katelyn","family":"Anderson","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mayo Clinic  Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avni","family":"Joshi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Allergy and Immunology Mayo Clinic  Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carilyn","family":"Wieland","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mayo Clinic  Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Tyring","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Texas Health Science Center  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Rady","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Texas Health Science Center  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megha","family":"Tollefson","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mayo Clinic  Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,4]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.14740\/jocmr2466w"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.5144\/0256-4947.2007.222"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-009-1131-9"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12663-011-0184-2"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.00368"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijabmr.IJABMR_252_18"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.180882"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.14463","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.14463","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.14463","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T17:32:43Z","timestamp":1693675963000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.14463"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,4]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1111\/pde.14463"],"URL":"https:\/\/doi.org\/10.1111\/pde.14463","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,4]]},"assertion":[{"value":"2020-05-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}