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This observation demonstrates that topically applied (non\u2010selective) beta\u2010blockers may induce blanched macules at the site of application, a side effect due to peripheral vasoconstriction of blood vessels by non\u2010selective beta\u20102 blockade. This side effect was linked due to overuse and was reversible. This case illustrates the importance of providing thorough instructions regarding topical propranolol application.<\/jats:p>","DOI":"10.1111\/pde.14475","type":"journal-article","created":{"date-parts":[[2020,12,4]],"date-time":"2020-12-04T15:07:53Z","timestamp":1607094473000},"page":"263-264","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["An infant with localized vasoconstriction following topical propranolol exposure for infantile hemangioma"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7512-154X","authenticated-orcid":false,"given":"Julie","family":"Saerens","sequence":"first","affiliation":[{"name":"Department of Dermatology University Hospital Brussels (UZ Brussel, UZB) Vrije Universiteit Brussel (VUB)  Jette Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Gutermuth","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Brussels (UZ Brussel, UZB) Vrije Universiteit Brussel (VUB)  Jette Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8700-480X","authenticated-orcid":false,"given":"Sherief R.","family":"Janmohamed","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Brussels (UZ Brussel, UZB) Vrije Universiteit Brussel (VUB)  Jette Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,4]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09848.x"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000477411"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-016-1635-x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13048"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e318267d3db"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000334778"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14963"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0162"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1994.tb00705.x"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13517"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12248"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12767"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.02.029"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-012-0928-9"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12869"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.14475","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.14475","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.14475","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T17:32:41Z","timestamp":1693675961000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.14475"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,4]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1111\/pde.14475"],"URL":"https:\/\/doi.org\/10.1111\/pde.14475","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,4]]},"assertion":[{"value":"2020-05-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}