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Somatic mosaic mutations underly the progressive nature of PWBs and explain the significant differences in response and heterogeneity of vessel architecture in the pediatric population when compared to the adult cohort. Here, we summarize a review of pediatric specific literature on the various light\u2010based treatment modalities, including pulsed dye laser, near\u2010infrared lasers, and intense pulsed light, providing the various indications, tips, advantages, and disadvantages for the pediatric dermatologist.<\/jats:p>","DOI":"10.1111\/pde.14503","type":"journal-article","created":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T08:39:22Z","timestamp":1609144762000},"page":"351-358","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Light\u2010based treatment of pediatric port\u2010wine birthmarks"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1505-8099","authenticated-orcid":false,"given":"Jennifer M.","family":"Tran","sequence":"first","affiliation":[{"name":"Department of Dermatology University of Wisconsin School of Medicine and Public Health Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen M.","family":"Kelly","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California Irvine Irvine CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth A.","family":"Drolet","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Wisconsin School of Medicine and Public Health Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7876-3791","authenticated-orcid":false,"given":"Andrew C.","family":"Krakowski","sequence":"additional","affiliation":[{"name":"Department of Dermatology St. Luke\u2019s University Health Network Easton PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa M.","family":"Arkin","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Wisconsin School of Medicine and Public Health Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.58.2.218"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.02.1167"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1991.tb01597.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.10.033"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15716"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000000785"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02314.x"},{"issue":"2","key":"e_1_2_6_9_1","article-title":"N. 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