{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:52:31Z","timestamp":1771462351797,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,1,24]],"date-time":"2021-01-24T00:00:00Z","timestamp":1611446400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/Objectives<\/jats:title><jats:p>Efficacy and safety data of scabies treatments in infants are limited. Although topical permethrin is used in the treatment of scabies in adults, it is not approved for use in infants younger than 2\u00a0months of age in many parts of the world. This study aimed to describe treatment practices in the management of scabies in infants younger than 2\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An online survey was developed and distributed to physicians worldwide through the Society of Pediatric Dermatology and the Pediatric Dermatology Research Alliance. Data collected included demographics, medication availability, experience using medications, deterrents to medication use, medication administration preferences, perceived and experienced medication side effects, and preferred treatment agent in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 57 physicians from seven countries responded. The majority of respondents were board\u2010certified in pediatric dermatology (48\/57, 84.2%) and resided in the United States (44\/57, 77.2%). Respondents had experience using permethrin (47\/57, 82.5%) and precipitated sulfur (35\/57, 61.4%) most frequently. Most (38\/57, 66.7%) preferred permethrin as their treatment of choice. Among those who did not use permethrin, potential side effects (8\/10, 80%) were most frequently reported as a deterrent from its use. However, only 4.3% (22\/47) of those who used permethrin reported side effects, including itching, erythema, and xerosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Permethrin is frequently used in the treatment of infants younger than 2\u00a0months with scabies. Furthermore, our results demonstrate that permethrin is the preferred treatment agent among sampled dermatologists for infants younger than 2\u00a0months. Few side effects were reported, and none were serious.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pde.14523","type":"journal-article","created":{"date-parts":[[2021,1,24]],"date-time":"2021-01-24T08:19:41Z","timestamp":1611476381000},"page":"431-435","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Treatment practices in the management of scabies in infants younger than two months"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6464-322X","authenticated-orcid":false,"given":"Cristina","family":"Thomas","sequence":"first","affiliation":[{"name":"Harvard Medicine\u2010Dermatology Combined Residency Training Program Harvard Medical School Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wingfield","family":"Rehmus","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Pediatrics University of British Columbia Vancouver BC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4921-2333","authenticated-orcid":false,"given":"Aileen Y.","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,24]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"World Health Organization.Scabies.https:\/\/www.who.int\/neglected_diseases\/diseases\/scabies\u2010and\u2010other\u2010ectoparasites\/en\/. Accessed November 4 2020"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004803"},{"issue":"4","key":"e_1_2_8_4_1","first-page":"CD012994","article-title":"Ivermectin and permethrin for treating scabies","volume":"2","author":"Rosumeck S","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"e_1_2_8_5_1","first-page":"1005","article-title":"Permethrin for scabies in children","volume":"56","author":"Albakri L","year":"2010","journal-title":"Can Fam Physician"},{"key":"e_1_2_8_6_1","unstructured":"Alpharma.Permethrin cream 5% approval package.https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/anda\/98\/074806ap.pdf. Published1998. 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Accessed November 1 2020."},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13255"},{"key":"e_1_2_8_11_1","volume-title":"Red Book: 2018\u20132021 Report of the Committee on Infectious Diseases","author":"American Academy of Pediatrics","year":"2018"},{"key":"e_1_2_8_12_1","volume-title":"Epidemiology and Management of Common Skin Diseases in Children in Developing Countries","author":"World Health Organization","year":"2005"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp052784"},{"key":"e_1_2_8_14_1","unstructured":"Taro Pharmaceuticals.Ovide (malathion) lotion 0.5% product insert.https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2011\/018613s017lbl.pdf. Published 2011. 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Accessed November 14 2020"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.14523","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.14523","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.14523","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T19:28:27Z","timestamp":1692300507000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.14523"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,24]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/pde.14523"],"URL":"https:\/\/doi.org\/10.1111\/pde.14523","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,24]]},"assertion":[{"value":"2020-11-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}