{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T03:51:25Z","timestamp":1788580285170,"version":"build-2803163510"},"reference-count":5,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,3,21]],"date-time":"2021-03-21T00:00:00Z","timestamp":1616284800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>As more therapeutic clinical trials focus on treatment of individual wounds in patients with recessive dystrophic epidermolysis bullosa, it has become crucial to understand the baseline clinical characteristics of these wounds. To investigate these features, we administered an RDEB\u2010specific wound survey. Forty participants reported on location, size, pain, infection frequency, wound type, and duration of 189 wounds; a subset of 22 participants reported on pruritus in 63 wounds. Increased wound size was significantly associated with increased pain, increased pruritus, longer wound duration, increased infection frequency, and patients with mutations resulting in truncated type VII collagen.<\/jats:p>","DOI":"10.1111\/pde.14576","type":"journal-article","created":{"date-parts":[[2021,3,22]],"date-time":"2021-03-22T02:49:12Z","timestamp":1616381352000},"page":"704-706","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Clinical characteristics associated with increased wound size in patients with recessive dystrophic epidermolysis bullosa"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9942-4564","authenticated-orcid":false,"given":"Daniel C.","family":"Solis","sequence":"first","affiliation":[{"name":"Department of Internal Medicine University of California Riverside Riverside CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily S.","family":"Gorell","sequence":"additional","affiliation":[{"name":"Department of Dermatology Stanford University School of Medicine Stanford CA USA"},{"name":"Department of Dermatology University of Cincinnati College of Medicine Cincinnati OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Teng","sequence":"additional","affiliation":[{"name":"Department of Dermatology Stanford University School of Medicine Stanford CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Barriga","sequence":"additional","affiliation":[{"name":"Department of Dermatology Stanford University School of Medicine Stanford CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaron","family":"Nazaroff","sequence":"additional","affiliation":[{"name":"School of Medicine University of California Irvine Irvine CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shufeng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology Stanford University School of Medicine Stanford CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Subica","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of California Riverside Riverside CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Biomedical Data Science Administration Stanford University Stanford CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Peter","family":"Marinkovich","sequence":"additional","affiliation":[{"name":"Department of Dermatology Stanford University School of Medicine Stanford CA USA"},{"name":"Veterans Affairs Medical Center Palo Alto CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Y.","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Stanford University School of Medicine Stanford CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.08.118"},{"key":"e_1_2_8_3_1","unstructured":"https:\/\/clinicaltrials.gov\/ct2\/results?cond=epidermolysis+bullosa. Accessed December 13 2020."},{"issue":"20","key":"e_1_2_8_4_1","first-page":"30442","article-title":"Patient\u2010reported outcomes and quality of life in recessive dystrophic epidermolysis bullosa: a global cross\u2010sectional survey","volume":"9622","author":"Eng VA","year":"2020","journal-title":"J Am Acad Dermatol"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12391"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2929"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.14576","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.14576","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.14576","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T18:24:36Z","timestamp":1693419876000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.14576"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,21]]},"references-count":5,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1111\/pde.14576"],"URL":"https:\/\/doi.org\/10.1111\/pde.14576","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,21]]},"assertion":[{"value":"2021-03-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}