{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:52:01Z","timestamp":1747187521482,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T00:00:00Z","timestamp":1618272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/Objectives<\/jats:title><jats:p>Nail alterations are commonly seen in cases of idiopathic clubfoot and may cause parental concern. The nature of and whether these changes are congenital or develop secondary to treatment has been poorly investigated. The aim of this study was to evaluate toenail morphology in clubfoot patients at presentation, to re\u2010evaluate them during the course of treatment for the clubfoot, and to analyze findings in the light of the few literature reports for healthy children of the same age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty infants (21 males and 9 females) with idiopathic clubfoot were prospectively enrolled at the Anna Meyer Children's University Hospital. Nails of affected and non\u2010affected feet were evaluated by a team of pediatric dermatologists at presentation and re\u2010evaluated once per patient during the bracing period of Ponseti treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Toenails of affected (47) and non\u2010affected (13) feet were abnormal at presentation in 43.3% of patients, in both clubfeet (40.4%) and non\u2010affected feet (38.5%), but most changes were physiologic or transitory alterations, commonly found in healthy children, with nail concavity (koilonychia) being the most common finding (29.7%). Changes were not related to clubfoot severity or laterality (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a0.05). In most (76.9%) unilateral cases, there was concordance of nail changes between clubfoot and non\u2010affected foot. At re\u2010evaluation (follow\u2010up time 410\u00a0\u00b1\u00a0207\u00a0days), nail problems were more frequent (53.3%); ingrown toenail was the most common (21.6%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The presence of nail alterations seems not to be caused by clubfoot pathology and could be related to unfavorable local condition in the brace.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pde.14609","type":"journal-article","created":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T02:27:40Z","timestamp":1618367260000},"page":"617-622","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Nail changes in children with idiopathic congenital clubfoot deformity"],"prefix":"10.1111","volume":"38","author":[{"given":"Manuele","family":"Lampasi","sequence":"first","affiliation":[{"name":"Ortopediatria Center for Education, Research and Patient Care in Paediatric Orthopedics Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diletta","family":"Bandinelli","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology University of Perugia R. Silvestrini Hospital Perugia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caterina Novella","family":"Abati","sequence":"additional","affiliation":[{"name":"Department of Paediatric Orthopedics Anna Meyer Children\u2019s Hospital Florence Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camilla","family":"Bettuzzi","sequence":"additional","affiliation":[{"name":"Department of Paediatric Orthopedics Anna Meyer Children\u2019s Hospital Florence Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giada","family":"Salvatori","sequence":"additional","affiliation":[{"name":"Ortopediatria Center for Education, Research and Patient Care in Paediatric Orthopedics Bologna Italy"},{"name":"Department of Paediatric Orthopedics Anna Meyer Children\u2019s Hospital Florence Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Bassi","sequence":"additional","affiliation":[{"name":"Dermatology Unit Department of Pediatrics Anna Meyer Children's Hospital Florence Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesare","family":"Filippeschi","sequence":"additional","affiliation":[{"name":"Dermatology Unit Department of Pediatrics Anna Meyer Children's Hospital Florence Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7277-3278","authenticated-orcid":false,"given":"Teresa","family":"Oranges","sequence":"additional","affiliation":[{"name":"Dermatology Unit Department of Pediatrics Anna Meyer Children's Hospital Florence Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,4,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2014.06.001"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0683-8"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.2.376"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2006.03.003"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2008.02592.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fas.2015.09.007"},{"volume-title":"Congenital Clubfoot: fundamentals of Treatment","year":"1996","author":"Ponseti IV","key":"e_1_2_7_8_1"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0b013e3182694f4d"},{"key":"e_1_2_7_10_1","first-page":"53","article-title":"A reliable and valid method of assessing the amount of deformity in the congenital clubfoot deformity","volume":"90","author":"Pirani S","year":"2008","journal-title":"J Bone Joint Surg Br"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000486020"},{"key":"e_1_2_7_12_1","first-page":"1","article-title":"Incomplete development of the nail of the hallux in the newborn","volume":"15","author":"Milano A","year":"2010","journal-title":"Dermatol Online J"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13978"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/783924"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13683"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.14609","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.14609","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.14609","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T18:22:59Z","timestamp":1693419779000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.14609"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,13]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1111\/pde.14609"],"URL":"https:\/\/doi.org\/10.1111\/pde.14609","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"type":"print","value":"0736-8046"},{"type":"electronic","value":"1525-1470"}],"subject":[],"published":{"date-parts":[[2021,4,13]]},"assertion":[{"value":"2021-04-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}