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In our practice, we have found the use of topical clobetasol to be effective to induce regression of cutaneous pyogenic granulomas. We present here a case of an adolescent patient with autism and two bleeding pyogenic granulomas who poorly tolerated a biopsy of the first lesion and could not tolerate subsequent procedures. Topical therapy with clobetasol effectively managed the second pyogenic granuloma, an approach representative of a noninvasive practice utilized in our clinic.<\/jats:p>","DOI":"10.1111\/pde.14698","type":"journal-article","created":{"date-parts":[[2021,7,17]],"date-time":"2021-07-17T05:38:45Z","timestamp":1626500325000},"page":"149-151","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Topical corticosteroids for noninvasive treatment of pyogenic granulomas"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4370-7300","authenticated-orcid":false,"given":"Danna","family":"Moustafa","sequence":"first","affiliation":[{"name":"Harvard Medical School Boston MA USA"},{"name":"Department of Dermatology Massachusetts General Hospital Boston MA 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