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DITRA is characterized by acute generalized pustular psoriasis (GPP), fever, systemic inflammation, and leukocytosis. We report the case of a 5\u2010year\u2010old girl with severe scalp and nail involvement with a rapid response to secukinumab.\n                  <\/jats:p>","DOI":"10.1111\/pde.14737","type":"journal-article","created":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T13:34:14Z","timestamp":1627911254000},"page":"1258-1263","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Rapid response to secukinumab in a 5\u2010year\u2010old with deficiency of the interleukin\u201036 receptor antagonist (DITRA) with severe scalp and nail involvement"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6263-4880","authenticated-orcid":false,"given":"Guo","family":"Jing","sequence":"first","affiliation":[{"name":"Department of Dermatology University of Hong Kong Shenzhen Hospital Shenzhen 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