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The early onset of the disease, prominent facial involvement, family history of an autosomal dominant trait, and poor response to conventional treatment are characteristics of CAPE that distinguish it from classical psoriasis and PRP. We describe the clinical features, family history, and response to therapy in three unrelated children with CAPE and compare these characteristics with those of previously described pediatric patients. Testing for <jats:italic>CARD14<\/jats:italic> mutations in children with early onset of features of psoriasis or pityriasis rubra pilaris and resistance to conventional therapy should be considered.<\/jats:p>","DOI":"10.1111\/pde.14779","type":"journal-article","created":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T02:20:44Z","timestamp":1630030844000},"page":"1237-1242","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["<i>CARD14<\/i>\u2010associated papulosquamous eruption (CAPE) in pediatric patients: Three additional cases and review of the literature"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8488-5675","authenticated-orcid":false,"given":"Cindy P.","family":"Frare","sequence":"first","affiliation":[{"name":"Department of Dermatology Hospital Alem\u00e1n Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alli J.","family":"Blumstein","sequence":"additional","affiliation":[{"name":"Departments of Dermatology and Pediatrics Northwestern University Feinberg School of Medicine Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6187-6549","authenticated-orcid":false,"given":"Amy S.","family":"Paller","sequence":"additional","affiliation":[{"name":"Departments of Dermatology and Pediatrics Northwestern University Feinberg School of Medicine Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lia","family":"Pieretti","sequence":"additional","affiliation":[{"name":"Dr \u00daraga Private Center for Skin Diseases Guayaquil Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith A.","family":"Choate","sequence":"additional","affiliation":[{"name":"Department of Genetics Yale University School of Medicine New Haven CT USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne M.","family":"Bowcock","sequence":"additional","affiliation":[{"name":"Dermatology, Oncological Sciences and Genetics &amp; 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