{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:54:36Z","timestamp":1772160876867,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T00:00:00Z","timestamp":1658707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000354","name":"Food Standards Agency","doi-asserted-by":"publisher","award":["TO7060"],"award-info":[{"award-number":["TO7060"]}],"id":[{"id":"10.13039\/501100000354","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004331","name":"Johnson and Johnson","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004331","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014364","name":"National Children's Research Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014364","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"publisher","award":["12\/RC\/2272"],"award-info":[{"award-number":["12\/RC\/2272"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"publisher","award":["15\/SP\/3091"],"award-info":[{"award-number":["15\/SP\/3091"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017291","name":"Health and Social Care Northern Ireland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017291","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010414","name":"Health Research Board","doi-asserted-by":"publisher","award":["223047\/Z\/21\/Z"],"award-info":[{"award-number":["223047\/Z\/21\/Z"]}],"id":[{"id":"10.13039\/100010414","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009036","name":"Canadian Institute for Theoretical Astrophysics","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009036","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Atopic dermatitis (AD) has a strong genetic basis. The objective of this study was to assess the association between parental atopy and AD development by 2\u2009years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A secondary data analysis of the BASELINE Birth Cohort study was performed (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a02183). Parental atopy was self\u2010reported at 2 months. Infants were examined for AD by trained health care professionals at 6, 12, and 24\u2009months. Variables extracted from the database related to skin barrier function, early skincare, parental atopy, and AD. Statistical analysis adjusted for potential confounding variables.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Complete data on AD status were available for 1505 children at 6, 12, and 24\u2009months. Prevalence of AD was 18.6% at 6 months, 15.2% at 12\u2009months, and 16.5% at 24\u2009months. Adjusted odds ratios (95% CIs) following multivariable analysis were 1.57 (1.09\u20132.25) at 6 months and 1.66 (1.12\u20132.46) at 12\u2009months for maternal AD; 1.90 (1.28\u20132.83) at 6 months and 1.85 (1.20\u20132.85) at 24\u2009months for paternal AD; 1.76 (1.21\u20132.56) at 6 months and 1.75 (1.16\u20132.63) at 12\u2009months for maternal asthma; and 1.70 (1.19\u20132.45) at 6 months, 1.86 (1.26\u20132.76) at 12\u2009months, and 1.99 (1.34\u20132.97) at 24\u2009months for paternal asthma. Parental rhinitis was only associated with AD with maternal rhinitis at 24\u2009months (aOR (95% CI): 1.79 (1.15\u20132.80)).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Parental AD and asthma were associated with increased risk of objectively diagnosed AD in offspring in this contemporary cohort.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pde.15090","type":"journal-article","created":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T22:09:38Z","timestamp":1658786978000},"page":"896-902","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Parental atopy and risk of atopic dermatitis in the first two years of life in the BASELINE birth cohort study"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7084-5293","authenticated-orcid":false,"given":"Cathal","family":"O'Connor","sequence":"first","affiliation":[{"name":"Paediatrics and Child Health Cork University Hospital  Cork Ireland"},{"name":"INFANT Research Centre University College Cork  Cork Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vicki","family":"Livingstone","sequence":"additional","affiliation":[{"name":"Paediatrics and Child Health Cork University Hospital  Cork Ireland"},{"name":"INFANT Research Centre University College Cork  Cork Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4997-9857","authenticated-orcid":false,"given":"Jonathan O'. B.","family":"Hourihane","sequence":"additional","affiliation":[{"name":"Paediatrics and Child Health Cork University Hospital  Cork Ireland"},{"name":"INFANT Research Centre University College Cork  Cork Ireland"},{"name":"Paediatrics and Child Health Royal College of Physicians of Ireland  Dublin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9048-2044","authenticated-orcid":false,"given":"Alan D.","family":"Irvine","sequence":"additional","affiliation":[{"name":"INFANT Research Centre University College Cork  Cork Ireland"},{"name":"Dermatology Children's Health Ireland at Crumlin  Dublin Ireland"},{"name":"Clinical Medicine Trinity College Dublin  Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0920-5291","authenticated-orcid":false,"given":"Geraldine","family":"Boylan","sequence":"additional","affiliation":[{"name":"Paediatrics and Child Health Cork University Hospital  Cork Ireland"},{"name":"INFANT Research Centre University College Cork  Cork Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2201-9912","authenticated-orcid":false,"given":"Deirdre","family":"Murray","sequence":"additional","affiliation":[{"name":"Paediatrics and Child Health Cork University Hospital  Cork Ireland"},{"name":"INFANT Research Centre University College Cork  Cork Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.11.029"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.4168\/aair.2015.7.2.101"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2016.06.002"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2017.02.006"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.11.015"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1767"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2003.034033"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102222.2003.01749.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.67.8.1018"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523\u20101747.ep12338475"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2012.05.054"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2017.0556"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.3.468"},{"key":"e_1_2_9_15_1","unstructured":"AB. MSN. Welcome to the BASELINE study.2008. Accessed February 17 2022.http:\/\/www.baselinestudy.net\/"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102133.1994.tb08532.x"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0039803"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD013534.pub2"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.15090","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.15090","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.15090","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T03:28:44Z","timestamp":1692588524000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.15090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,25]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1111\/pde.15090"],"URL":"https:\/\/doi.org\/10.1111\/pde.15090","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.742251407.793595819","asserted-by":"object"}]},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,25]]},"assertion":[{"value":"2022-03-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}