{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T05:57:14Z","timestamp":1773295034298,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,9,24]],"date-time":"2022-09-24T00:00:00Z","timestamp":1663977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"Abstract<\/jats:title>Linear Cowden nevus, also known as linear PTEN nevus, is a type of epidermal nevus, first described in 2007, which is seen in patients with PTEN hamartoma tumor syndrome. It is considered to be a type 2 form of segmental mosaicism, and we suggest that it has certain clinical features that distinguish it from epidermal nevi seen in similar conditions, such as Proteus syndrome. We present a case of linear Cowden nevus in a 4\u2010year\u2010old boy and review the literature.<\/jats:p>","DOI":"10.1111\/pde.15116","type":"journal-article","created":{"date-parts":[[2022,9,24]],"date-time":"2022-09-24T08:29:42Z","timestamp":1664008182000},"page":"179-181","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Verrucous epidermal nevus as a manifestation of a type 2 mosaic PTEN<\/i><\/scp> mutation in Cowden syndrome"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2241-5664","authenticated-orcid":false,"given":"Adri\u00e0","family":"Plana\u2010Pla","sequence":"first","affiliation":[{"name":"Dermatology Department, Hospital Universitari Germans Trias I Pujol (HUGTiP), Badalona Barcelona Spain"},{"name":"Departament de Medicina Universitat Aut\u00f2noma de Barcelona. Badalona Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Condal","sequence":"additional","affiliation":[{"name":"Dermatology Department, Hospital Universitari Germans Trias I Pujol (HUGTiP), Badalona Barcelona Spain"},{"name":"Departament de Medicina Universitat Aut\u00f2noma de Barcelona. Badalona Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ane","family":"Jaka","sequence":"additional","affiliation":[{"name":"Dermatology Department, Hospital Universitari Germans Trias I Pujol (HUGTiP), Badalona Barcelona Spain"},{"name":"Departament de Medicina Universitat Aut\u00f2noma de Barcelona. Badalona Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Blanco","sequence":"additional","affiliation":[{"name":"Clinical Genetics and Genetic Counseling Unit, Clinical Genetics Service, Northern Metropolitan Clinical Laboratory Germans Trias i Pujol University Hospital (HUGTiP), Badalona Barcelona Spain"},{"name":"Clinical Genomics Research Unit Germans Trias i Pujol Research Institute (IGTP\u2010PMPPC), Badalona Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Castellanos","sequence":"additional","affiliation":[{"name":"Clinical Genomics Research Unit Germans Trias i Pujol Research Institute (IGTP\u2010PMPPC), Badalona Barcelona Spain"},{"name":"Clinical Genomics Unit, Clinical Genetics Service, Northern Metropolitan Clinical Laboratory Germans Trias i Pujol University Hospital (HUGTiP), Badalona Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Bielsa","sequence":"additional","affiliation":[{"name":"Dermatology Department, Hospital Universitari Germans Trias I Pujol (HUGTiP), Badalona Barcelona Spain"},{"name":"Departament de Medicina Universitat Aut\u00f2noma de Barcelona. Badalona Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,9,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.31743"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5201823"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djt277"},{"key":"e_1_2_6_5_1","first-page":"133","article-title":"Linear Cowden nevus: a new distinct epidermal nevus","volume":"17","author":"Happle R","year":"2007","journal-title":"Eur J Dermatol"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep39348"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07196.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1104017"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/9.5.765"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.31273"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2021.08.029"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.15116","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.15116","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.15116","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T16:25:03Z","timestamp":1692548703000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.15116"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,24]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["10.1111\/pde.15116"],"URL":"https:\/\/doi.org\/10.1111\/pde.15116","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,24]]},"assertion":[{"value":"2022-04-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}