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The resulting buildup can manifest as neuropsychiatric symptoms and photosensitive blistering eruptions on sun\u2010exposed skin. We report a case of VP in a 9\u2010year\u2010old girl with many confounding medical factors that warranted alternative explanations for her cutaneous lesions. VP has been reported infrequently in the pediatric population and is associated with more severe neuropsychiatric outcomes compared to adult\u2010onset disease.<\/jats:p>","DOI":"10.1111\/pde.15150","type":"journal-article","created":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T13:08:22Z","timestamp":1664543302000},"page":"326-329","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A 9\u2010year\u2010old girl with blisters on the hands and face: An early presentation of variegate porphyria"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2406-9761","authenticated-orcid":false,"given":"Aref","family":"Moshayedi","sequence":"first","affiliation":[{"name":"School of Medicine Virginia Commonwealth University  Richmond Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark C.","family":"Mochel","sequence":"additional","affiliation":[{"name":"Departments of Pathology and Dermatology Virginia Commonwealth University  Richmond Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy N.","family":"Brooks","sequence":"additional","affiliation":[{"name":"Department of Pediatric Genetics Virginia Commonwealth University  Richmond Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Laver","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology and Stem Cell Transplantation Virginia Commonwealth University  Richmond Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly S.","family":"Salkey","sequence":"additional","affiliation":[{"name":"Department of Dermatology Virginia Commonwealth University  Richmond Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,9,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/45.7.932"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/0471142905.hg1720s86"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2019.04.008"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.17219\/acem\/58955"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13052\u2010022\u201001215\u20108"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(84)92298\u20100"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102133.1990.tb08272.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445\u20105994.1990.tb01320.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12071"},{"issue":"6","key":"e_1_2_6_11_1","first-page":"722","article-title":"Variegate porphyria in South Africa, 1688\u20101996\u2014new developments in an old disease","volume":"87","author":"Hift RJ","year":"1997","journal-title":"S Afr Med J"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10545\u2010012\u20109544\u20104"},{"key":"e_1_2_6_13_1","unstructured":"American Porphyria Foundation.Drug Safety Database. 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