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We identified a germline compound heterozygous <jats:italic>DOCK6<\/jats:italic> mutation and a somatic mosaic <jats:italic>NRAS<\/jats:italic> Q61R mutation in the giant congenital melanocytic nevus. This report will increase clinician awareness of SCALP syndrome and augment the literature in characterizing this rare syndrome, including its genetic background.<\/jats:p>","DOI":"10.1111\/pde.15184","type":"journal-article","created":{"date-parts":[[2022,12,2]],"date-time":"2022-12-02T07:33:46Z","timestamp":1669966426000},"page":"523-527","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<scp>SCALP<\/scp> syndrome\u00a0with a germline heterozygous <i>DOCK6<\/i> mutation and somatic mosaic <i>NRAS<\/i><scp>Q61R<\/scp> mutation"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6157-5746","authenticated-orcid":false,"given":"Summer N.","family":"Meyer","sequence":"first","affiliation":[{"name":"Department of Dermatology University of California Davis  Sacramento California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elanee M.","family":"Simmons","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California Davis  Sacramento California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D.","family":"McPherson","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine University of California Davis  Sacramento California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0683-5001","authenticated-orcid":false,"given":"Smita","family":"Awasthi","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California Davis  Sacramento California USA"},{"name":"Department of Pediatrics University of California Davis  Sacramento California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7010-5516","authenticated-orcid":false,"given":"Maija","family":"Kiuru","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California Davis  Sacramento California USA"},{"name":"Department of Pathology &amp; 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