{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T23:24:13Z","timestamp":1792106653732,"version":"4.4.0"},"reference-count":6,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T00:00:00Z","timestamp":1668556800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A healthy 12\u2010month\u2010old female presented with relapsing and remitting urticaria since birth that was resistant to treatment with antihistamines. A thorough history revealed extensive rheumatic disease on the father's side of the family, and subsequent genetic testing was positive for a missense variant of <jats:italic>NLRP3<\/jats:italic>, indicating cryopyrin\u2010associated periodic fever syndrome (CAPS). CAPS encompasses a spectrum of diseases, all related to a defect in the same gene; manifestations vary in severity and presentation, but most are associated with recurrent rash and fever. Because the patient's only presenting symptom was rash, this case highlights the importance of having a high index of suspicion for cryopyrin\u2010associated periodic fever syndrome in infants with persistent, early urticaria.<\/jats:p>","DOI":"10.1111\/pde.15188","type":"journal-article","created":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T08:49:19Z","timestamp":1668588559000},"page":"532-533","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Presentation of cryopyrin\u2010associated periodic fever syndrome as chronic, afebrile urticaria in a 12\u2010month\u2010old female"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4894-3609","authenticated-orcid":false,"given":"Lauren A.","family":"Fitzgerald","sequence":"first","affiliation":[{"name":"Texas A&amp;M College of Medicine  Bryan Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeeha","family":"Drissi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Baylor Scott and White\/Texas A&amp;M  Temple Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirstin","family":"Sepulveda","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease Baylor Scott and White  Temple Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Hovland","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Baylor Scott and White  Temple Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia J.","family":"Hendrick","sequence":"additional","affiliation":[{"name":"Department of Dermatology Baylor Scott and White\/Texas A&amp;M  Temple Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gueorgui","family":"Dubrocq","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease Baylor Scott and White  Temple Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.10509"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10875\u2010019\u201000638\u2010z"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555\u20101322"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525\u20101470.2012.01812.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI71543"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.02.040"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.15188","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.15188","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.15188","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T04:51:18Z","timestamp":1697086278000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.15188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,16]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1111\/pde.15188"],"URL":"https:\/\/doi.org\/10.1111\/pde.15188","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,16]]},"assertion":[{"value":"2022-06-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}