{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:51:31Z","timestamp":1747187491140,"version":"3.40.5"},"reference-count":5,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T00:00:00Z","timestamp":1683676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Infantile hemangiomas (IHs) are the most common pediatric vascular tumors, although their genetic etiology is largely unknown. Congenital capillary malformations (CMs) are associated with known somatic pathogenic variants, including <jats:italic>GNAQ<\/jats:italic>, <jats:italic>GNA11<\/jats:italic>, <jats:italic>PIK3CA<\/jats:italic>, and <jats:italic>PIK3R1<\/jats:italic>. Co\u2010occurrence of a facial CM such as port wine stain and IH is not associated with any recognized vascular anomaly syndromes and rarely reported in the literature. We describe a case of a 5\u2010week\u2010old female patient with a large facial CM and extensive IHs of the lower lip, airway, and orbit who presented with airway compromise and responded to propranolol therapy.<\/jats:p>","DOI":"10.1111\/pde.15340","type":"journal-article","created":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T05:25:09Z","timestamp":1683782709000},"page":"1142-1144","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A case of large airway and orbital hemangiomas with facial capillary malformation"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-1542-0891","authenticated-orcid":false,"given":"Margaret Ann","family":"Kreher","sequence":"first","affiliation":[{"name":"College of Medicine University of Florida  Gainesville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liza H.","family":"Siegel","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonid","family":"Shmuylovich","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,10]]},"reference":[{"unstructured":"International Society for the Study of Vascular Anomalies.ISSVA Classification of Vascular Anomalies.2018Accessed March 8 2023. Available at \u201cissva.org\/classification\u201d.","key":"e_1_2_6_2_1"},{"doi-asserted-by":"publisher","key":"e_1_2_6_3_1","DOI":"10.1056\/NEJMoa1213507"},{"doi-asserted-by":"publisher","key":"e_1_2_6_4_1","DOI":"10.3390\/ijms20092243"},{"doi-asserted-by":"publisher","key":"e_1_2_6_5_1","DOI":"10.1111\/ced.14428"},{"doi-asserted-by":"publisher","key":"e_1_2_6_6_1","DOI":"10.1111\/pde.12384"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.15340","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T15:38:30Z","timestamp":1704209910000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.15340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,10]]},"references-count":5,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1111\/pde.15340"],"URL":"https:\/\/doi.org\/10.1111\/pde.15340","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"type":"print","value":"0736-8046"},{"type":"electronic","value":"1525-1470"}],"subject":[],"published":{"date-parts":[[2023,5,10]]},"assertion":[{"value":"2023-02-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}