{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:12:30Z","timestamp":1791389550809,"version":"4.3.3"},"reference-count":5,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T00:00:00Z","timestamp":1703635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Recently, alopecia areata (AA) treatment via the Janus kinase (JAK)\u2010signal transducer and activator of transcription pathway has been reported. However, as baricitinib, a JAK1\/2 inhibitor is only approved for adult patients, children, and adolescent patients still lack treatment options. We present a case that showed improvement of severe AA in an adolescent patient on upadacitinib, which has been approved by the Food and Drug Administration (FDA) for use in patients with rheumatoid disease or atopic dermatitis (AD) in children aged 12\u2009years or older and weighing 40\u2009kg or more. Herein, we suggest that upadacitinib can be a good alternative for adolescent patients with AA, particularly those who may also have AD.<\/jats:p>","DOI":"10.1111\/pde.15504","type":"journal-article","created":{"date-parts":[[2023,12,28]],"date-time":"2023-12-28T03:44:15Z","timestamp":1703735055000},"page":"356-358","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Improvement of severe alopecia areata in an adolescent patient on upadacitinib"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6210-7039","authenticated-orcid":false,"given":"Gi Ung","family":"Ha","sequence":"first","affiliation":[{"name":"Department of Dermatology, School of Medicine Kyungpook National University, Kyungpook National University Hospital  Daegu South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4315-8134","authenticated-orcid":false,"given":"Jin Ho","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology, School of Medicine Kyungpook National University, Kyungpook National University Hospital  Daegu South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1706-007X","authenticated-orcid":false,"given":"Yong Hyun","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, School of Medicine Kyungpook National University, Kyungpook National University Hospital  Daegu South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,27]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16808"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S172638"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/2050313X221138452"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-023-00889-0"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.2340\/actadv.v103.5578"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.15504","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T14:21:02Z","timestamp":1738333262000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.15504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,27]]},"references-count":5,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1111\/pde.15504"],"URL":"https:\/\/doi.org\/10.1111\/pde.15504","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,27]]},"assertion":[{"value":"2023-08-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}