{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:20:39Z","timestamp":1787016039055,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T00:00:00Z","timestamp":1714348800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Acrochordons or skin tags are common benign skin growths. Several studies explored the relationship between obesity and metabolic syndrome in adults but remains unexplored in children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a single\u2010center retrospective cohort study of outpatient dermatology patients between 1 January 2000 to 1 January 2021. Children under 18\u2009years old diagnosed with acrochordons using diagnostic codes International Classification of Diseases, 10th Revision (ICD\u201010)\u2009L91.8 and 9th Revision (ICD\u20109) 701.8 were included. We collected patient demographics, past medical history, laboratory values, vital signs, and physical exam. Body mass index (BMI) was calculated and stratified into categories based on the Center for Disease Control's BMI\u2010for\u2010Age Growth Charts. Metabolic syndrome was diagnosed when three of the five criteria were met. Data were propensity\u2010matched and compared with NHANES (National Health and Nutrition Examination Survey), which offered a generalizable sample to the US population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Fifty\u2010five patients under 18\u2009years old with a diagnosis of acrochordons were mostly Caucasian (76%) and female (64%). The mean BMI was 27.3, with 49.5% categorized as obese and 20% as overweight. The mean age of diagnosis was 10.1\u2009years. Acrochordon predominantly appeared in the axilla. In our cohort, three patients (5.5%) met the criteria for metabolic syndrome. The prevalence of obesity (42% vs. 21%), type 2 diabetes mellitus (4.8% vs. 0.6%), hyperlipidemia (8.1% vs. 0%), and hypertension (1.6% vs. 0%) was greater in our cohort compared with NHANES.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Like the adult population, acrochordons may serve as marker for metabolic disease in the pediatric population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pde.15639","type":"journal-article","created":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T20:58:20Z","timestamp":1714424300000},"page":"660-666","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The relationship between acrochordons, obesity, and metabolic syndrome in the pediatric population: A retrospective cohort study"],"prefix":"10.1111","volume":"41","author":[{"given":"Rachel K.","family":"Greene","sequence":"first","affiliation":[{"name":"Department of Dermatology University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suma","family":"Gangidi","sequence":"additional","affiliation":[{"name":"Carle Illinois College of Medicine  Urbana Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond","family":"Zhao","sequence":"additional","affiliation":[{"name":"Trinity Health  Livonia Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessie M.","family":"Nelson","sequence":"additional","affiliation":[{"name":"University of Michigan Medical School  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Harms","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mio","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","unstructured":"StiermanB AffulJ CarrollMD et al.National Health and Nutrition Examination Survey 2017\u2013March 2020 prepandemic data files\u2014development of files and prevalence estimates for selected health outcomes. National Health Statistics Reports 158.2021. doi:10.15620\/cdc:106273","DOI":"10.15620\/cdc:106273"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI142245"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/2141\u20109248.129040"},{"key":"e_1_2_8_5_1","first-page":"1","article-title":"2000 CDC growth charts for the United States: methods and development","volume":"246","author":"Kuczmarski RJ","year":"2002","journal-title":"Vital Health Stat"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.157.8.821"},{"key":"e_1_2_8_7_1","unstructured":"National Health and Nutrition Examination Survey (NHANES). CDC\/NCHS.2024. Accessed December 9 2022.https:\/\/health.gov\/healthypeople\/objectives\u2010and\u2010data\/data\u2010sources\u2010and\u2010methods\/data\u2010sources\/national\u2010health\u2010and\u2010nutrition\u2010examination\u2010survey\u2010nhanes"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10238\u2010009\u20100086\u20105"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.4396"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2021\u2010053708"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2013.09.008"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1530\/EC\u201023\u20100235"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.14978"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2014\/10350.4853"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.12.070"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.21037\/tp.2017.10.02"},{"key":"e_1_2_8_17_1","volume-title":"StatPearls","author":"Pandey A","year":"2024"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s005920200014"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12895\u2010020\u201000111\u20100"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.3233\/HAB\u2010200426"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1996.d01-923.x"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1590\/s0365\u201005962012000100031"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11154\u2010016\u20109378\u20108"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12456"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.15639","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T11:07:38Z","timestamp":1721646458000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.15639"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,29]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1111\/pde.15639"],"URL":"https:\/\/doi.org\/10.1111\/pde.15639","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,29]]},"assertion":[{"value":"2023-09-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}