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Catastrophic APS (CAPS) is a severe form with higher morbidity and mortality in which there occurs widespread thrombosis in multiple organs and hence warrants early diagnosis and aggressive management. We report a case of pediatric CAPS with extensive cutaneous involvement precipitated by infection successfully treated with the combination of high dose systemic corticosteroids, antibiotics, long\u2010term anticoagulation, and wound care.<\/jats:p>","DOI":"10.1111\/pde.15642","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T04:53:26Z","timestamp":1716526406000},"page":"1148-1151","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pediatric catastrophic antiphospholipid syndrome with extensive skin involvement"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2832-1538","authenticated-orcid":false,"given":"Swetalina","family":"Pradhan","sequence":"first","affiliation":[{"name":"Department of Dermatology All India Institute of Medical Sciences  Patna India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asmita","family":"Sinha","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kailash hospital  Noida India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2308-8493","authenticated-orcid":false,"given":"Gaurav","family":"Dash","sequence":"additional","affiliation":[{"name":"Department of Dermatology All India Institute of Medical Sciences  Patna India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishnu","family":"Ojha","sequence":"additional","affiliation":[{"name":"Department of Dermatology All India Institute of Medical Sciences  Patna India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,23]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/ayu.AYU_57_16"},{"key":"e_1_2_5_3_1","first-page":"9","article-title":"Catastrophic antiphospholipid syndrome: a clinical review","volume":"3","author":"Nayer A","year":"2014","journal-title":"J Nephropathol"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0961203312460722"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0000000000000426"},{"key":"e_1_2_5_6_1","first-page":"508","article-title":"The catastrophic antiphospholipid syndrome","volume":"19","author":"Asherson RA","year":"1992","journal-title":"J Rheumatol"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/1759720X20910855"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2013.10.004"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13312-021-2104-y"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-004-1734-3"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-211001"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2018.09.006"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.41891"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2014.03.002"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2013.05.004"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.15642","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T08:56:16Z","timestamp":1732092976000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.15642"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,23]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1111\/pde.15642"],"URL":"https:\/\/doi.org\/10.1111\/pde.15642","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,23]]},"assertion":[{"value":"2023-11-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}