{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T04:45:55Z","timestamp":1789447555582,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T00:00:00Z","timestamp":1728950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Trichotillomania (TTM) significantly increases the risk of psychiatric comorbidities. Sparse research in pediatric populations necessitates larger studies to assess these risks. This study investigates the risk of developing psychiatric comorbidities in pediatric TTM patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This case\u2013control study assessed pediatric patients (&lt;\u200918\u2009years old) with TTM diagnosed between May 18, 2013, and January 1, 2024, using US\u2010based data from the TriNetX global research network. TTM patients (ICD\u201010 diagnostic category F63.3) aged 18 years or younger at diagnosis and control patients (ICD\u201010 code Z00.129) matched for age, sex, race, and ethnicity were assessed. Propensity score matching yielded 16,590 patients in each cohort. The analysis assessed subsequent diagnoses of ADHD, conduct disorders, tic disorders, obsessive\u2010compulsive disorder, anxiety disorders, dissociative, stress\u2010related, and somatoform disorders, mood disorders, and suicide attempts compared to controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>TTM patients under 18 years exhibited significantly greater risks of subsequent diagnoses for ADHD (OR: 2.002; CI 1.841\u20132.178; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), conduct disorders (OR: 3.668; 3.2\u20133.668; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), tic disorders (OR: 2.247; 1.826\u20132.765; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), obsessive\u2010compulsive disorder (OR: 11.047; 8.822\u201313.832; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), anxiety disorders (OR: 3.583; 3.387\u20133.7; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), dissociative, stress\u2010related, and somatoform disorders (OR: 6.179; 3.935\u20139.701; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), mood disorders (OR: 2.476; 2.288\u20132.68; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), and suicide attempts (OR: 1.81; 1.121\u20132.924; <jats:italic>p<\/jats:italic>\u2009=\u20090.0139) compared to controls. TTM patients had the greatest risk of psychiatric diagnosis 1\u2009year postindex event.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Pediatric TTM patients have higher psychiatric comorbidity risks, necessitating timely intervention and comprehensive management. Dermatologists can facilitate access to behavioral and pharmacological care, enhancing patient outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pde.15791","type":"journal-article","created":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T01:48:34Z","timestamp":1729043314000},"page":"61-66","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Psychiatric Comorbidities in Pediatric Trichotillomania: A\u00a0Multicenter Cohort Study"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4565-6855","authenticated-orcid":false,"given":"Margaux","family":"Games","sequence":"first","affiliation":[{"name":"Drexel University College of Medicine  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zane","family":"Sejdiu","sequence":"additional","affiliation":[{"name":"Drexel University College of Medicine  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erum N.","family":"Ilyas","sequence":"additional","affiliation":[{"name":"Department of Dermatology Drexel University College of Medicine  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,15]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders: DSM\u20105, 5th ed","author":"American Psychiatric Association, and American Psychiatric Association Publishing","year":"2017"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1586\/ern.11.93"},{"issue":"10","key":"e_1_2_10_4_1","first-page":"415","article-title":"Estimated Lifetime Prevalence of Trichotillomania in College Students","volume":"52","author":"Christenson G. A.","year":"1991","journal-title":"Journal of Clinical Psychiatry"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2012.12.019"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DBP.0b013e31818d4328"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920\u2010012\u20100269\u20108"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583\u2010199511000\u201000011"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/08039488.2022.2052179"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0887\u20106185(99)00028\u20106"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/16506070701223230"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02353354"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.24869\/psyd.2018.79"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000371809"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2021.675468"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2018.3658"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000510524"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13954"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.15791","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T14:30:04Z","timestamp":1749133804000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.15791"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,15]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1111\/pde.15791"],"URL":"https:\/\/doi.org\/10.1111\/pde.15791","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,15]]},"assertion":[{"value":"2024-03-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}