{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T09:36:44Z","timestamp":1761989804880,"version":"3.41.0"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T00:00:00Z","timestamp":1740960000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Midface toddler excoriation syndrome (MiTES) is a rare dermatological condition characterized by chronic, self\u2010inflicted excoriations of the midface, often leading to significant scarring and hyperpigmentation. It typically affects young children, with a male predominance. MiTES is linked to genetic mutations in the <jats:italic>PRDM12<\/jats:italic> gene. Treatment approaches vary, including topical antimicrobials, emollients, steroids, and oral medications aimed at reducing scratching impulses. However, responses are inconsistent, and many patients show only partial or moderate improvement. This review consolidates current knowledge of MiTES, emphasizing its clinical features, genetic basis, and management strategies.<\/jats:p>","DOI":"10.1111\/pde.15917","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T20:55:47Z","timestamp":1741726547000},"page":"469-474","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Midface Toddler Excoriation Syndrome (<scp>MiTES<\/scp>): A Review"],"prefix":"10.1111","volume":"42","author":[{"given":"Varniraj","family":"Patel","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology All India Institute of Medical Sciences  Rajkot Gujarat India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepika","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Maulana Azad Medical College and Lok Nayak Hospital  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maitri","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology GMERS Medical College and Hospital  Vadodara Gujarat India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vaishnavi","family":"Modi","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Maulana Azad Medical College and Lok Nayak Hospital  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishna Deb","family":"Barman","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Maulana Azad Medical College and Lok Nayak Hospital  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7135-8494","authenticated-orcid":false,"given":"Vishal","family":"Gaurav","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Maulana Azad Medical College and Lok Nayak Hospital  Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,3,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12997"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16893"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.05.036"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.14081"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijdvl.IJDVL_323_19"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/ija.ija_321_23"},{"issue":"1","key":"e_1_2_9_8_1","first-page":"335","article-title":"Mid\u2010Face Toddler Excoriation Syndrome (MiTES)","volume":"33","author":"Hosthota A.","year":"2023","journal-title":"Journal of Pakistan Association of Dermatologists"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijpd.ijpd_37_22"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjd\/ljae151"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3308"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2019.02.097"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2011.04.006"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2767"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.15917","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T06:45:57Z","timestamp":1751525157000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.15917"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,3]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1111\/pde.15917"],"URL":"https:\/\/doi.org\/10.1111\/pde.15917","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"type":"print","value":"0736-8046"},{"type":"electronic","value":"1525-1470"}],"subject":[],"published":{"date-parts":[[2025,3,3]]},"assertion":[{"value":"2024-11-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}