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In this case report, a 12\u2010year\u2010old female with EBP was successfully treated with upadacitinib at a dosage of 15\u2009mg once daily for a period of 12\u2009weeks, after which the frequency was changed to every other day. A review of the literature identified 19 cases successfully treated with a Janus kinase inhibitor (JAKi) suggesting that JAKis are a promising option for EBP patients.<\/jats:p>","DOI":"10.1111\/pde.15963","type":"journal-article","created":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T00:22:39Z","timestamp":1745367759000},"page":"1221-1226","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Successful Use of Upadacitinib in Treating a Child With Epidermolysis Bullosa Pruriginosa: A Case Report and Literature Review"],"prefix":"10.1111","volume":"42","author":[{"given":"Xumei","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Dermatology, Beijing Children's Hospital Capital Medical University, National Center for Children's Health  Beijing China"},{"name":"Key Laboratory of Major Diseases in Children, Ministry of Education  Beijing 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