{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T20:41:54Z","timestamp":1780605714881,"version":"3.54.1"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,7,19]],"date-time":"2025-07-19T00:00:00Z","timestamp":1752883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,19]],"date-time":"2025-07-19T00:00:00Z","timestamp":1752883200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Trichostasis spinulosa (TS) is a follicular disorder involving the retention of numerous hairs in a dilated follicle, primarily reported in adults. Drug\u2010induced TS and pediatric TS are rarely described in the literature. We report a four\u2010year\u2010old female with an unusual presentation of TS localized in the groin and vulva. Interestingly, the patient's TS seemed to worsen with the introduction of clonidine for her autism spectrum disorder (ASD). The rash improved significantly once clonidine was held, and recurred when clonidine was re\u2010started. This case highlights that TS should be considered in pediatric patients, even in atypical locations, and clonidine may exacerbate TS.<\/jats:p>","DOI":"10.1111\/pde.16016","type":"journal-article","created":{"date-parts":[[2025,7,19]],"date-time":"2025-07-19T09:25:35Z","timestamp":1752917135000},"page":"125-127","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Trichostasis Spinulosa: A Case Report of an Unusual Presentation in the Groin of a Pediatric Patient on Clonidine"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0727-1909","authenticated-orcid":false,"given":"Katherine","family":"Aw","sequence":"first","affiliation":[{"name":"Faculty of Medicine University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3370-2612","authenticated-orcid":false,"given":"S. Dresden","family":"Glockler\u2010Lauf","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Faculty of Medicine University of Ottawa and the Ottawa Hospital  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1939-7338","authenticated-orcid":false,"given":"Dina","family":"El Demellawy","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Faculty of Medicine University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4471-5281","authenticated-orcid":false,"given":"Carmen","family":"Liy\u2010Wong","sequence":"additional","affiliation":[{"name":"Division of Dermatology and Rheumatology Children's Hospital of Eastern Ontario, University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13110"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000486541"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1996.tb00731.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000509993"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2002.01508.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/idoj.idoj_544_23"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1998.tb02486.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-7753.82126"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-6175.2001.00954.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.2019.04.180212"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-7753.188032"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-7753.111201"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.16016","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.16016","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.16016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T01:29:59Z","timestamp":1769736599000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.16016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,19]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1111\/pde.16016"],"URL":"https:\/\/doi.org\/10.1111\/pde.16016","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,19]]},"assertion":[{"value":"2025-01-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}