{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T15:21:34Z","timestamp":1769786494917,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T00:00:00Z","timestamp":1755043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T00:00:00Z","timestamp":1755043200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Psoriasis is a skin disease characterized by erythematous and scaly lesions, influenced by genetic and environmental factors. Hirschsprung disease (HD) is a congenital disorder associated with gut microbiome dysbiosis, which can trigger inflammatory skin conditions. We report a case of psoriasis vulgaris in a male infant with HD whose skin lesions completely resolved after HD treatment. This case highlights a potential link between HD\u2010related gut dysbiosis and psoriasis.<\/jats:p>","DOI":"10.1111\/pde.16036","type":"journal-article","created":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T11:40:02Z","timestamp":1755085202000},"page":"141-144","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["From Gut Dysbiosis to Skin Inflammation: Exploring the\u00a0Hirschsprung's Disease\u2010Psoriasis Link"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-1233-0373","authenticated-orcid":false,"given":"Harun","family":"Yildirim","sequence":"first","affiliation":[{"name":"Department of Dermatology Firat University Hospital  Elazig Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6190-5124","authenticated-orcid":false,"given":"Betul","family":"Demir","sequence":"additional","affiliation":[{"name":"Department of Dermatology Firat University Hospital  Elazig Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5140-8618","authenticated-orcid":false,"given":"Unal","family":"Bakal","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Firat University Hospital  Elazig Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1877-7267","authenticated-orcid":false,"given":"Ozlem","family":"Ucer","sequence":"additional","affiliation":[{"name":"Department of Pathology Firat University Hospital  Elazig Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3672-630X","authenticated-orcid":false,"given":"Nur Sena","family":"Sevinc","sequence":"additional","affiliation":[{"name":"Department of Dermatology Firat University Hospital  Elazig Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4064-4287","authenticated-orcid":false,"given":"Ebru Aydin","family":"Yildirim","sequence":"additional","affiliation":[{"name":"Clinic of Dermatology Fethi Sekin City Hospital  Elazig Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2022.11124"},{"key":"e_1_2_10_3_1","first-page":"32965813","volume-title":"Hirschsprung Disease","author":"Lotfollahzadeh S.","year":"2025"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10051037"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijpd.IJPD_72_18"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346\u20108138.17049"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2016.2932"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572\u2010023\u201000465\u2010y"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.19935"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2021.155750"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.5114\/ada.2018.78028"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2020.108537"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.14016"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15951"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.4168\/aair.2020.12.1.137"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/bies.201600008"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2014.03.019"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2024.1330903"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.4014\/jmb.2312.12031"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13797"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.issn.0578\u20101426.2019.10.011"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.16036","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.16036","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.16036","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T01:29:34Z","timestamp":1769736574000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.16036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,13]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1111\/pde.16036"],"URL":"https:\/\/doi.org\/10.1111\/pde.16036","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,13]]},"assertion":[{"value":"2025-04-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}