{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T16:04:12Z","timestamp":1769789052767,"version":"3.49.0"},"reference-count":5,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:00:00Z","timestamp":1754092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:00:00Z","timestamp":1754092800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Jarisch\u2010Herxheimer (JH) reaction is a known side effect involving the worsening of pre\u2010existing skin lesions accompanied by systemic symptoms such as fever, chills, headache, and myalgias. This reaction typically occurs following the initiation of anti\u2010syphilitic therapy but has also been reported with other antimicrobial therapies, such as those for leptospirosis. This case describes the occurrence of a JH\u2010like reaction after the first intake of griseofulvin for the treatment of tinea capitis in a 14\u2010year\u2010old patient. Due to the rarity of the case, the purpose of this report is to raise awareness of the potential for such reactions with systemic antifungal therapies and to provide guidance on their management.<\/jats:p>","DOI":"10.1111\/pde.70001","type":"journal-article","created":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T07:39:35Z","timestamp":1754120375000},"page":"201-203","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Jarisch\u2010Herxheimer\u2010Like Reaction After Griseofulvin Oral Intake for Tinea Infection Treatment"],"prefix":"10.1111","volume":"43","author":[{"given":"Francesca","family":"Gaudiello","sequence":"first","affiliation":[{"name":"Section of Dermatology, Department of Clinical Medicine and Surgery University of Naples Federico II  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonia","family":"Salsano","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Clinical Medicine and Surgery University of Naples Federico II  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Gallo","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Clinical Medicine and Surgery University of Naples Federico II  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7997-1784","authenticated-orcid":false,"given":"Nello","family":"Tommasino","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Clinical Medicine and Surgery University of Naples Federico II  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimiliano","family":"Scalvenzi","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Clinical Medicine and Surgery University of Naples Federico II  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8445-7135","authenticated-orcid":false,"given":"Antonio","family":"Portarapillo","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Clinical Medicine and Surgery University of Naples Federico II  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,2]]},"reference":[{"key":"e_1_2_1_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13244"},{"key":"e_1_2_1_8_3_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071\u2010200607050\u201000007"},{"key":"e_1_2_1_8_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2015.4293"},{"key":"e_1_2_1_8_5_1","first-page":"1009","article-title":"Herxheimer's Reactions at the Onset of Treatment of the Folds by Griseofulvin","volume":"67","author":"Lestrade","year":"1960","journal-title":"Bulletin de la Soci\u00e9t\u00e9 Fran\u00e7aise de Dermatologie et de Syphiligraphie"},{"key":"e_1_2_1_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2023.107555"}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.70001","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.70001","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.70001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T01:30:08Z","timestamp":1769736608000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.70001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,2]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1111\/pde.70001"],"URL":"https:\/\/doi.org\/10.1111\/pde.70001","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,2]]},"assertion":[{"value":"2024-12-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}