{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T16:04:12Z","timestamp":1769789052744,"version":"3.49.0"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,17]],"date-time":"2025-08-17T00:00:00Z","timestamp":1755388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,8,17]],"date-time":"2025-08-17T00:00:00Z","timestamp":1755388800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Epidermolysis bullosa simplex (EBS) is a genetic condition characterized by skin fragility and blistering due to minimal mechanical trauma. EBS\u2010KLHL24, a rare subtype, arises from pathogenic variants in the\n                    <jats:italic>KLHL24<\/jats:italic>\n                    gene and has unique clinical features, including systemic involvement. We present a case of a 16\u2010year\u2010old patient with EBS\u2010KLHL24 exhibiting novel clinical findings, including significant oral blistering, hyperkeratotic papules, ocular involvement, and lichenified reticulate flexural scarring. This case expands the EBS\u2010KLHL24 phenotype and highlights the importance of accurate diagnosis, early genetic confirmation, and multidisciplinary care to improve understanding of this disorder.\n                  <\/jats:p>","DOI":"10.1111\/pde.70005","type":"journal-article","created":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T01:35:46Z","timestamp":1755480946000},"page":"154-157","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Novel Clinical Observations Indicative of Epidermolysis Bullosa Simplex Associated With\n                    <i>KLHL24<\/i>"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0440-4830","authenticated-orcid":false,"given":"Madison","family":"Anzelc","sequence":"first","affiliation":[{"name":"Dermatology Residency Program OhioHealth Riverside Methodist Hospital  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Pedraza","sequence":"additional","affiliation":[{"name":"The University of Toledo College of Medicine and Life Sciences  Toledo Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joy","family":"Mosser\u2010Goldfarb","sequence":"additional","affiliation":[{"name":"Nationwide Children's Hospital and the Ohio State College of Medicine  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2020.05.001"},{"key":"e_1_2_7_3_1","volume-title":"GeneReviews","author":"So J. 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