{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T16:04:10Z","timestamp":1769789050356,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:00:00Z","timestamp":1760313600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:00:00Z","timestamp":1760313600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Upper\u2010facial capillary malformation (CM) may be concerning for Sturge\u2013Weber syndrome (SWS). Use of screening magnetic resonance imaging (MRI) for neuroradiographic findings of SWS is controversial. MRI within a few months of life may allow for prompt reassurance, preventive treatments, and avoidance of contrast and sedation. However, false\u2010negative MRI before 1\u2009year of age has been reported. We examined the ability of early MRI to predict seizure development in infants with upper\u2010facial CM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Infants with forehead or temple CM presenting to the Sturge\u2013Weber Clinic at Boston Children's Hospital from 2012 to 2022 were identified. The records were reviewed for clinical features and for findings from MRI performed before 1\u2009year of age (MRI 1) and repeated around or after 2\u2009years of age (MRI 2). Patients with seizures before MRI 1 or with a diagnosis of nevus simplex were excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty\u2010three patients with forehead or temple CM without seizures before MRI 1 were identified. MRI 1 was abnormal in 20\/33 and normal in 13\/33. Fourteen of 20 patients with abnormal MRI 1 developed seizures. Of the 13 patients with normal MRI 1, 11 underwent MRI 2. In patients with MRI 2, 3\/11 developed SWS\u2010related abnormalities, but none (0\/11) developed seizures. The remaining 2 patients with normal MRI 1 also did not develop seizures. Mean follow\u2010up age was 6.1\u2009years (0.83\u201315\u2009years).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Early, high\u2010quality non\u2010contrast 3\u2009T MRI may screen for seizure development in infants with upper\u2010facial CM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/pde.70032","type":"journal-article","created":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T04:51:55Z","timestamp":1760417515000},"page":"56-63","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Early Magnetic Resonance Imaging as a Screen for Sturge\u2013Weber Syndrome\u2010Related Seizures in Infants With Upper\u2010Facial Capillary Malformations"],"prefix":"10.1111","volume":"43","author":[{"given":"Mia A.","family":"Mologousis","sequence":"first","affiliation":[{"name":"Tufts University School of Medicine  Boston Massachusetts USA"},{"name":"Department of Dermatology Boston Children's Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4466-1863","authenticated-orcid":false,"given":"Racquel A.","family":"Bitar","sequence":"additional","affiliation":[{"name":"Department of Dermatology Boston Children's Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna L.","family":"Pinto","sequence":"additional","affiliation":[{"name":"Department of Neurology Boston Children's Hospital  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne M.","family":"Rispoli","sequence":"additional","affiliation":[{"name":"Harvard Medical School  Boston Massachusetts USA"},{"name":"Department of Radiology Boston Children's Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2545-2754","authenticated-orcid":false,"given":"Marilyn G.","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Boston Children's Hospital  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-197702000-00014"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2021.04.013"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/NRL.0b013e318220c5b6"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2011.01485.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1350"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2018.04.009"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13598"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2018.04.005"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/088307389501000113"},{"issue":"1","key":"e_1_2_10_11_1","first-page":"53","article-title":"Sturge\u2010Weber 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