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Hydrophilic polymer and potassium ferrate (HPPF) provides a rapid alternative that achieves hemostasis, seals the wound, and potentially reduces procedural anxiety in pediatric and adolescent patients while also eliminating the need for suture removal. In this retrospective study comparing sutures and HPPF for 3\u20135\u2009mm punch biopsies, minimal complications were observed overall, with sutures causing one instance of dehiscence or bleeding, whereas HPPF did not. Additionally, suture use was overrepresented in head and neck sites, whereas HPPF was more frequently used for back sites, demonstrating that HPPF offers a cost\u2010effective and efficient closure method in pediatric patients.<\/jats:p>","DOI":"10.1111\/pde.70057","type":"journal-article","created":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:11:01Z","timestamp":1762161061000},"page":"369-372","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Retrospective Analysis Evaluating Hydrophilic Polymer and Potassium Ferrate as an Alternative to Sutures for Pediatric Punch Biopsies"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3947-1956","authenticated-orcid":false,"given":"Randy F.","family":"Ko","sequence":"first","affiliation":[{"name":"The University of New Mexico School of Medicine  Albuquerque New Mexico USA"},{"name":"Division of Molecular Medicine, Department of Internal Medicine The University of New Mexico Health Science Center  Albuquerque New Mexico USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4314-7814","authenticated-orcid":false,"given":"Melanie S.","family":"Jun","sequence":"additional","affiliation":[{"name":"The University of New Mexico School of Medicine  Albuquerque New Mexico USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly N.","family":"White","sequence":"additional","affiliation":[{"name":"Department of Dermatology The University of New Mexico School of Medicine  Albuquerque New Mexico USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aimee C.","family":"Smidt","sequence":"additional","affiliation":[{"name":"Department of Dermatology The University of New Mexico School of Medicine  Albuquerque New Mexico USA"},{"name":"Department of Pediatrics The University of New Mexico School of Medicine  Albuquerque New\u00a0Mexico USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John R.","family":"Durkin","sequence":"additional","affiliation":[{"name":"Department of Dermatology The University of New Mexico School of Medicine  Albuquerque New Mexico USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13377"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346\u20108138.16585"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000003163"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2022.08.007"},{"key":"e_1_2_10_6_1","unstructured":"FAQ's \u201cWoundSeal.com \u2013 Stop Bleeding Instantly \u201d2024 https:\/\/woundseal.com\/faqs\/."},{"key":"e_1_2_10_7_1","unstructured":"WOUNDSEAL Hemostatic Agent (1199074) \u201c4\/PK. BettyMills.com \u201d2024 https:\/\/www.bettymills.com\/woundseal\u2010hemostatic\u2010agent\u2010woundseal\u20104\u2010per\u2010box\u2010individual\u2010packet\u2010hydrophilic\u2010polymer\u2010potassium\u2010ferrate\u20104\u2010pk\u201083406100004\u2010mon811970pk."}],"container-title":["Pediatric Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.70057","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/pde.70057","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pde.70057","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T04:27:00Z","timestamp":1775881620000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pde.70057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,3]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1111\/pde.70057"],"URL":"https:\/\/doi.org\/10.1111\/pde.70057","archive":["Portico"],"relation":{},"ISSN":["0736-8046","1525-1470"],"issn-type":[{"value":"0736-8046","type":"print"},{"value":"1525-1470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,3]]},"assertion":[{"value":"2024-12-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}