{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T04:56:34Z","timestamp":1775883394778,"version":"3.50.1"},"reference-count":38,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis in infancy, often misdiagnosed due to overlap with infectious\u00a0and inflammatory conditions. We review existing literature on neonatal and infantile PG and present a case of a previously\u00a0healthy 6\u2010month\u2010old male with rapidly progressive ulcerative lesions involving the face, scalp, extremities,\u00a0and\u00a0hard\u00a0palate. Histopathology revealed a dense dermal neutrophilic infiltrate, and an extensive workup was unremarkable.\u00a0The\u00a0patient responded rapidly and completely to systemic corticosteroid monotherapy. Published cases similarly\u00a0highlight idiopathic presentations and favorable outcomes with corticosteroids as first\u2010line therapy. This case underscores the\u00a0importance of recognizing PG in infants with rapidly progressive skin ulcers, even in the absence of systemic disease.<\/jats:p>","DOI":"10.1111\/pde.70096","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T11:01:00Z","timestamp":1763636460000},"page":"300-303","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Infantile Pyoderma Gangrenosum: A Rare and Challenging Case Presentation With an Updated Literature Review"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9802-3280","authenticated-orcid":false,"given":"Alexis","family":"Tracy","sequence":"first","affiliation":[{"name":"Department of Dermatology Duke University  Durham North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kali","family":"Morrissette","sequence":"additional","affiliation":[{"name":"Department of Dermatology Duke University  Durham North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Kroshinsky","sequence":"additional","affiliation":[{"name":"Department of Dermatology Duke University  Durham North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12990"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1984.01650420067018"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13471"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.08.016"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2017.5980"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/5971706"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/bf02002902"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.24953\/turkjped.2023.714"},{"issue":"6","key":"e_1_2_8_10_1","first-page":"702","article-title":"Treatment of Refractory Pyoderma Gangrenosum With Infliximab in a 17\u2010Month\u2010Old Boy","volume":"9","author":"Bobbitt S. 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