{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T19:02:50Z","timestamp":1779649370698,"version":"3.53.1"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Dermatology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Acute generalized exanthematous pustulosis (AGEP) is a rare, drug\u2010induced hypersensitivity reaction that can mimic other serious febrile exanthems when pustule formation is delayed. We present a 16\u2010year\u2010old male who developed fever, diffuse erythema, and hypotension after amoxicillin exposure, initially raising concern for toxic shock syndrome. Classic pustules emerged several days into hospitalization, leading to a diagnosis of AGEP supported by clinical scoring. This case highlights the diagnostic challenges of AGEP in its early stages and underscores the importance of considering it in the differential for febrile rashes, particularly after recent beta\u2010lactam antibiotic use.<\/jats:p>","DOI":"10.1111\/pde.70098","type":"journal-article","created":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T00:49:57Z","timestamp":1763772597000},"page":"711-714","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Acute Generalized Exanthematous Pustulosis Mimicking Toxic Shock Syndrome in a Pediatric Patient"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3628-0952","authenticated-orcid":false,"given":"Amy","family":"Liao","sequence":"first","affiliation":[{"name":"Division of Dermatology, Department of Medicine Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harrison","family":"Shawa","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leigh","family":"Compton","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4667-7220","authenticated-orcid":false,"given":"Liza","family":"Siegel","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine Washington University School of Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102133.2007.08183.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2021.5390"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ski2.74"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600\u20100560.2001.028003113.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI12118"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20104632.2012.05704.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2022.02.009"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.paed.2022.03.004"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17081214"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11020397"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/1203475417701421"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2020-235846"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000511369"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.14704"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2009.01001.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000529218"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392\u2010025\u201002178\u2010y"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13434"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102133.2010.09967.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.36281"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.5114\/pdia.2014.40938"},{"key":"e_1_2_7_23_1","unstructured":"Centers for Disease Control and Prevention \u201cMultisystem Inflammatory Syndrome in Children (MIS\u2010C) Associated with SARS\u2010CoV\u20102 Infection: 2023 Case Definition. 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